diabetes Flashcards

1
Q

how many americans have diabetes

A

30 million

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2
Q

how many americans dont know they have diabetes

A

1 in 4

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3
Q

how many americans are pre diabetic

A

1 in 3 (90% dont know)

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4
Q

prediabetes fasting glucose level

A

between 100-125 mg/dL

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5
Q

pre diabetes glucose level after 75 g oral glucose challenge

A

140-199 mg/dL

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6
Q

pre diabetes HbA1C

A

5.7-6.4

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7
Q

assume that _____% of patients may display baseline dsyglycemia

A

more than 30%

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8
Q

what can surgery do to pre diabetics

A

hyperglycemia (stress)

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9
Q

diabetics have problems metabolizing….

A

carbs

proteins

lipids

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10
Q

how does glucose enter a cell

A

insulin binds to alpha chains on cell membrane

beta chains are phosphorylated

intracellular tyrosine kinase activated

insulin receptor substrates are activated

synthesis of various substances including glucose transport protein

glucose transport protein binds to cell membrane, glucose can enter now

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11
Q

normal blood sugar

A

75-100

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12
Q

when normal glucose transport is inhibited, blood glucose levels…..

A

rise

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13
Q

full blown diabetes HbA1c

A

more than 6.5

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14
Q

controlled diabetes HbA1c

A

less than 7

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15
Q

how many DM2 patients have no comorbidities

A

only 14%

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16
Q

most common comorbities DM2 (5)

A

obesity

CV dz

HTN

dyslipidemia

kidney dz

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17
Q

most common cause of mortality in diabetic pts

A

cardiovascular dz

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18
Q

what CV condition is poorly tolerated by diabetic pts

A

tachycardia

10x increase risk of death if HR more than 105 for 5 min in post op period

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19
Q

obesity has what other problem associated

A

OSA, GERD, airway management

20
Q

t/f: HTN has a greater effect on mortality than glycemic control

21
Q

insulin dependent diabetics with kidney disease at risk for hypo or hyper glycemia

22
Q

CKD pts with DM can’t do what

A

take oral medications like metformin

23
Q

a rapid reduction in HbA1c has what result

A

study showed increased mortality in drastic reduction in hyperglycemic levels

24
Q

SAMBA recommendation for safe BG level

A

less than 180

25
intra-operative hyperglycemia can result in...(5)
dehydration ketoacidosis hyperosmolar hyperglycemic state delayed wound healing wound infection
26
how often to check BG
at beginning of appt after two hours each subsequent hour at end of appt
27
how does a diabetic get hypoglycemic
taking their meds skipping breakfast long dental appointments inability to eat after surgery
28
signs and symptoms of hypoglycemia
confusion/combativeness weakness fatigue sweating palpitations
29
ddx for hypoglycemia
stroke MI dementia drug OD/ under dose
30
when do signs of hypoglycemia show up (what BG)
45-55
31
what is red flag BG for hypoglycemia
70
32
BG of less than 70 tx
give 15 g fast acting carb
33
BG of less than 50 tx
give 30 mg fast acting carb
34
examples of 15 g of carbs
1/2 cup apple juice or non diet pop small apple or orange 6 hard candies, 1 tablespoon jelly
35
if you weigh 100 lbs 1 g of ingested glucose will raise BG by
5 mg/dL
36
if you weigh 150 lbs 1 g of ingested glucose will raise BG by
4 mg/dL
37
if you weigh 200 lbs 1 g of ingested glucose will raise BG by
3 mg/dL
38
giving 50 mL of dextrose 50% IV will raise BG
75-125 mg/dL
39
what do you do for unconscious hypoglycemic pt
if you have IV: 50 mL 50% dextrose no IV: 1 unit glucagon subcutaneously
40
signs and symptoms of hyperglycemia
fatigue vision disturbances nausea excessive thirst polyuria
41
tx for hyperglycemia
find out pts insulin routine, if you dont know assume 60 units
42
the 1800 rule
divide patients daily insulin requirement into 1800 1 unit of rapid acting insulin will drop the BG by that many points
43
aspart brand name
novolog
44
lispro brand name
humalog
45
glulisine brand name
apidra
46
rapid acting insulins
aspart lispro glulisine