diabetes Flashcards

1
Q

how many americans have diabetes

A

30 million

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2
Q

how many americans dont know they have diabetes

A

1 in 4

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3
Q

how many americans are pre diabetic

A

1 in 3 (90% dont know)

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4
Q

prediabetes fasting glucose level

A

between 100-125 mg/dL

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5
Q

pre diabetes glucose level after 75 g oral glucose challenge

A

140-199 mg/dL

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6
Q

pre diabetes HbA1C

A

5.7-6.4

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7
Q

assume that _____% of patients may display baseline dsyglycemia

A

more than 30%

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8
Q

what can surgery do to pre diabetics

A

hyperglycemia (stress)

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9
Q

diabetics have problems metabolizing….

A

carbs

proteins

lipids

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10
Q

how does glucose enter a cell

A

insulin binds to alpha chains on cell membrane

beta chains are phosphorylated

intracellular tyrosine kinase activated

insulin receptor substrates are activated

synthesis of various substances including glucose transport protein

glucose transport protein binds to cell membrane, glucose can enter now

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11
Q

normal blood sugar

A

75-100

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12
Q

when normal glucose transport is inhibited, blood glucose levels…..

A

rise

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13
Q

full blown diabetes HbA1c

A

more than 6.5

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14
Q

controlled diabetes HbA1c

A

less than 7

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15
Q

how many DM2 patients have no comorbidities

A

only 14%

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16
Q

most common comorbities DM2 (5)

A

obesity

CV dz

HTN

dyslipidemia

kidney dz

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17
Q

most common cause of mortality in diabetic pts

A

cardiovascular dz

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18
Q

what CV condition is poorly tolerated by diabetic pts

A

tachycardia

10x increase risk of death if HR more than 105 for 5 min in post op period

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19
Q

obesity has what other problem associated

A

OSA, GERD, airway management

20
Q

t/f: HTN has a greater effect on mortality than glycemic control

A

true

21
Q

insulin dependent diabetics with kidney disease at risk for hypo or hyper glycemia

A

hypo

22
Q

CKD pts with DM can’t do what

A

take oral medications like metformin

23
Q

a rapid reduction in HbA1c has what result

A

study showed increased mortality in drastic reduction in hyperglycemic levels

24
Q

SAMBA recommendation for safe BG level

A

less than 180

25
Q

intra-operative hyperglycemia can result in…(5)

A

dehydration

ketoacidosis

hyperosmolar hyperglycemic state

delayed wound healing

wound infection

26
Q

how often to check BG

A

at beginning of appt

after two hours

each subsequent hour

at end of appt

27
Q

how does a diabetic get hypoglycemic

A

taking their meds

skipping breakfast

long dental appointments

inability to eat after surgery

28
Q

signs and symptoms of hypoglycemia

A

confusion/combativeness

weakness

fatigue

sweating

palpitations

29
Q

ddx for hypoglycemia

A

stroke

MI

dementia

drug OD/ under dose

30
Q

when do signs of hypoglycemia show up (what BG)

A

45-55

31
Q

what is red flag BG for hypoglycemia

A

70

32
Q

BG of less than 70 tx

A

give 15 g fast acting carb

33
Q

BG of less than 50 tx

A

give 30 mg fast acting carb

34
Q

examples of 15 g of carbs

A

1/2 cup apple juice or non diet pop

small apple or orange

6 hard candies, 1 tablespoon jelly

35
Q

if you weigh 100 lbs 1 g of ingested glucose will raise BG by

A

5 mg/dL

36
Q

if you weigh 150 lbs 1 g of ingested glucose will raise BG by

A

4 mg/dL

37
Q

if you weigh 200 lbs 1 g of ingested glucose will raise BG by

A

3 mg/dL

38
Q

giving 50 mL of dextrose 50% IV will raise BG

A

75-125 mg/dL

39
Q

what do you do for unconscious hypoglycemic pt

A

if you have IV: 50 mL 50% dextrose

no IV: 1 unit glucagon subcutaneously

40
Q

signs and symptoms of hyperglycemia

A

fatigue

vision disturbances

nausea

excessive thirst

polyuria

41
Q

tx for hyperglycemia

A

find out pts insulin routine, if you dont know assume 60 units

42
Q

the 1800 rule

A

divide patients daily insulin requirement into 1800

1 unit of rapid acting insulin will drop the BG by that many points

43
Q

aspart brand name

A

novolog

44
Q

lispro brand name

A

humalog

45
Q

glulisine brand name

A

apidra

46
Q

rapid acting insulins

A

aspart

lispro

glulisine