antibiotics Flashcards
why are cidal drugs preferred
less dependent on host immune system
take effect more quickly
maintain effect longer
exact dosing not as critical
good for prophylaxis (destroy bacteria)
which has more post antibiotic effects: static or cidal
statis
post antibiotic effect
persistant suppression of bacterial growth after brief exposure to abtc
may be due to DNA alteration
when is a loading dose helpful
if drug half life is less than 3 hours
if you need therapeutic dose in less than 12 hours
MIC
minimum dose that will prevent visible growth of bacteria in culture
is rebound infection common in oral/facial infections
no
nephrotoxic abtcs
penicililin, ahminoglycosides
neurotoxic abtcs
ahminoglycosides (ototoxic)
cross allergy btw PCN and cephalasporins
10-15%
superinfection more common with..
young and old
use of broad spectrum abtcs
what abtcs can cause c diff
cephalasporins
ampicillin
clindamycin
procaine and benzathine are…
penicillin G formulations
are methicillin, oxacillin, dicloxacillin indicated for odontogenic infections
no only if proven to be staph
is amoxicillin b lactamase resistant
no
first gen cephs cover:
strep/staph
PEK
