Diabetes Flashcards

1
Q

4 things occuring when the body thinks its starving from type 1 diabetes

A

increased gluconeogenesis
increased fatty acid oxidation
acetyl coa builds up
increased ketone body production

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2
Q

what is needed to diagnose metabolic syndromq

A
3 of 
waist circumference 
hdl cholesterol
serum triglyceride
serum glucose
blood pressure
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3
Q

Normal pre diabetiic and diabetic aic

A
  1. 5-5.6
  2. 7-6.4
  3. 5 and above
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4
Q

4 effects of hyperglycemia

A

diabetic reinopathy
arherosclerosis
diabetic neuropathy
diabetic nephrophathy

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5
Q

8 parts of ominous octet

A
impaired insulin 
increased glucagon 
increased HGP
neurotransmitter dysfunction
dereased glucose upate
increased glucose reabsorption
increased lipolysis
decreesed incretin effect
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6
Q

What does incretin do (GLP1)

A

Stimulates the pancreas to inhibit glucagon release and increase insulin release ( incr b cell proliferation

Also works on brain for fullness feeling and stomach for decreased gastric emptying

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7
Q

What therapudinc do we have relating to GLP 1

A

GLP analog sub in incretin

inibitors for blocking dpp4 (which is what inactives GLP-1)

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8
Q

What can you see with increased exercise

A

improved insulin sensitivity
decreased glucose levels
dec ldl tag and cholesterol
inc HDL

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9
Q

polymorphism and other risk factors for type 1 diabetes

A

HLA genes
PTPN
CTLA
Preproinsulin

viral triggers (rubella coxackie mumps)
Associated w/ other immune conditions
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