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Biochemistry Block 3 > Amino Acid Products > Flashcards

Amino Acid Products Flashcards

1
Q

Products of Tyrosine

A

Dopamine,
Norepinephrine,
Epinephrine
Melanin

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2
Q

Where is Dopamine Made

A

Brain
Sympathetic Nerve Axons
Adrenal Glands

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3
Q

What type of Molecule is Dopamine and what is linked to it

A

Neurotransmitter/Hormone

Dysfunction linked to Parkinson’s and other diseases

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4
Q

What can be used to convert to tyrosine

A

Phenylalanine

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5
Q

What enzyme/cofactor is needed for Tyrosine to L-Dopa

A

Tyrosine Hydroxylase

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6
Q

What is the path from Tyrosine to dopamine

A

Tyrosine to LDOPA to Dopamine

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7
Q

What is the path to make Noreinephrine

A

Tyrosine to LDOPA to Dopamine to Norepinephrine

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8
Q

What type of molecule is Norepinephrine

A

Neurotransmitter/hormone

mediates fight or flight

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9
Q

Where is Norepinephrine made

A

Sympathetic Nerve axons and adrenal glands

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10
Q

What is the path to make Epinephrine

A

Tyrosine to LDOPA to Dopamine to Norepinephrine to Epinephrine

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11
Q

What Enzyme/ factor is needed to go from Norepinephrine to Epinephrine

A

Phenylethanolamine N-methyltransferase

Using SAM

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12
Q

What is unique about the production of Melanin (tyrosine to L-Dopa)

A

In MelanocytesTyrosinase not tyrosine hydroxylase converts Tyrosine to L-DOPA

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13
Q

What enzyme and factor is used in the conversion of Tyrosine to LDOPA in Melanocytes

A

Tyrosinase

Cu 2+ dependent

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14
Q

What enzyme and factor is used to make Dopa quinone

A

Tyrosinase

Cu2+ dependent

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15
Q

What is the path of Tyrosine to Melanin

A

Tyrosine to LDOPA to Dopaquinone to Melanin

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16
Q

What is the role of melanin

A

Pigment

17
Q

What are the Products of Tryptophan

A

Serotonin, Melatonin, and NAD/NADP

18
Q

What is the path to make Seratonin

A

Tryptophan to Seratonin

19
Q

What Molecule is seratonin and what is its role

A

Neurotransmitter

regulates move

20
Q

Where is seratonin found in the body

A

Mainly in brain

21
Q

What is seen with seratonin deficiency

A

Depression
Insomnia
Migranes
others

22
Q

What is seen with Excess Seratonin

A 
Hypertension
Tacycardia
Dilated Pupils
Heavy sweating 
Confusion
Agitation/Restlessness
Tachypnea
others
23
Q

What is the process to make Melatonin

A

Tryptophan to seratonin to melatonin

24
Q

What molecule is melatonin and its role

A

Hormone

Circadian rhythm

25
Q

Where is melatonin produced

A

Brain specifically Pineal gland

26
Q

What is seen with Melatonin deficiency

A

Anxiety/Mood disorders, Insomnia, Lowered basal body temp, Elevated estrogen/progesterone ratio, Immune suppression (assoc w. cancer), others

27
Q

What is seen with excess Melatonin

A

Hypotension, Low adrenal and thyroid function, Seasonal affective disorder, lowered estrogen/progesterone ratio, others

28
Q

What are the product of glutamate

A

GABA (y-aminobutyrate)

Biochemistry Block 3 (7 decks)

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