Diabetes

Question 2

what can cause a falsely positive high A1C? (1+3)

Answer 2

Anything that slows down the body’s ability to break down RBCs including:
1. Anemias (untreated Fe, vitamin B12, folate)
2. Kidney disease
3. Hypertriglyceridemia

Question 3

what can cause a falsely positive low A1C? (1+3)

Answer 3

Anything that speeds up the breakdown of RBCS:
1. anemia being treated with supplementation
2. Blood donation
3. Pregnancy
4. Hemolysis (autoimmune etiology and meds (ribvarin, interferon alpha, etc))
5. Erythropoietin treatment
6. Dialysis

Question 4

goal for preprandial capillary plasma glucose

Answer 4

80-130mg/dL

Question 5

goal for peak postprandial capillary plasma glucose level?

Answer 5

less than 180

Question 6

what SGLT-2 inhibitor had an association of increased risk of bone fractures?

Answer 6

canagliflozin

Question 7

what puts a patient at increased risk of volume depletion/hypotension on SGLT-2 inhibitors?

Answer 7

concomitant use with diuretics