Diabetes Flashcards

1
Q

What are the two types of blood glucose test

A

capillary blood test
venous plasma blood glucose

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2
Q

What is the limit of plasma glucose in a random test

A

11.1 mmol/l
below 200mg / dl

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3
Q

What is fasting limit glucose at normal level

A

below
5.5 mmo/l
100 mg/dl

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4
Q

What is fasting limit glucose at prediabetic level

A

below 6.9
100 - 125mg / dl

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5
Q

What is fasting limit glucose at diabetic level

A

7 mmol / l >
126>

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6
Q

What is the normal level of a 2 hour post prandial test

A

<7.8
below 140

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7
Q

What is prediabetic level of a 2 hour post prandial

A

7.8 - 11 mmo/l
140 - 199 mg/dl

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8
Q

What is the diabetic level of a 2 hour post prandial

A

11.1 mmol/l or more
200mg / dl

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9
Q

main cause of diabetes type 1

A

Polygenic autoimmune disorder which leads to destruction of the β cells in the Islets of Langerhans of the pancreas, resulting in insulin deficiency

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10
Q

Main cause of type 2 diabetes

A

A polygenic disorder which leads to a decrease in the mass of β cells in the islets of langerhans, leading to a reduced secretion of insulin and insulin resistance

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11
Q

what are the main test we can use to diagnose diabetes

A

Urine dipstick
Rand venous plasma glucose test
Fasting venous plasma glucose test
oral glucose tolerance test
glycogen haemoglobulin levels

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12
Q

what is the gold standard test

A

oral glucose tolerance test

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13
Q

how is an oral glucose tolerance test carried out

A

fasting blood sugar
drink sweet drink
take blood samples every 30 minutes or 1 blood after 2 hours

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14
Q

Short term complications of diabetes

A

Hypoglycaemia
Ketoacidosis
Hyperosmolar hyperglycaemic state

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15
Q

long term complications of diabetes

A

cardiovascular disease
diabetic retinopathy
diabetic nephropathy
diabetic neuropathy

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16
Q

what is the blood glucose level that indicates hypoglycaemia

A

<4mmol

17
Q

9 symptoms of hypoglycaemia

A

Physical

Shaky
Sweaty
Fast Heart beat
Impaired vision

Feeling

Headache
Hungry
Fatigued
Irritable
Anxious

18
Q

Name 6 causes of hypoglycaemia

A

too much insulin prescribed

insulin absorbed more rapidly than normal

lipohypertrophy at injection site

reduced clearance of insulin owing to renal failure

decreased insulin requirement due to missed or delayed meals

failure to recognize symptoms

19
Q

Treatment of hypoglycaemia (Conscious then unconscious)

A

Glucose suplements if conscious
- drink
- tablet
- gel

if unconscious
- im or sc glucagon to break down the glycogen stored in the liver

20
Q

Define nocturnal hypoglycaemia

A

hypogylcaemia caused by

  • skipping meals
  • accidental overdose
  • alcohol or exercising in the evening
21
Q

what is diabetic ketoacidosis

A

severe emergency where dont have enough insulin to allow blood sugar into your cells for use as energy. Instead, your liver breaks down fat for fuel

22
Q

What are the Ketoacidosis causes

A

loose appetite and stop taking insulin as to prevent hypoglycaemia

infections need insulin so body can fight the infection

non compliance

23
Q

What are the symptoms of ketoacidosis

A

Polyurea
Polydipsia
Polyphagia
Fatigue
Blurred vision
Ketone breath
Labourered breathing

24
Q

What is the treatment of diabetic ketoacidosis

A

iv rehydration
insulin infusion
careful correction of electrolyte balance

25
Q

what is diabetic neuropathy

A

nerve damage caused by daibetes and poor glycaemic control

26
Q

what are 3 types of neuropathy

A

sensory
autonomic
motor

(think the different neurones)

27
Q

what is sensory neuropathy

A

lack of feeling or numbness in extremities

28
Q

what is autonomic neuropathy

A

can be things such as

ED
Incontinence
Irregular heart rate
Abnormal sweating
Gastroparesis

29
Q

what is motor neuropathy

A

muscle weakness
twitching
cramp

30
Q

Treatment for diabetic neuropathy

A

Tricyclic antidepressents
Duloxetine
VGCC ligands

if not tollerated try switching

31
Q

How can we minimise risk of diabetic complications in eye

A

annual eye screening to montor retina
keep blood glucose within normal range
maintain normal blood pressure
seek advise if blurred vision

32
Q

Treatment for retinopathy

A

laser surgery to improve circulation

anti vascular endothelial growth factor intro ocular injection to prevent inappropriate growth of blood vessels

intra ocular corticosteroid implant to inhibit inflammation and VEGF