Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

GU BLOCK > DEVELOPMENT: Reproductive Development > Flashcards

DEVELOPMENT: Reproductive Development Flashcards

1
Q

Male and Female reproductive systems and the urinary system develop from the same early structures:

A

●Urogenital ridge

●Mesonephric duct

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Some structures that form within the urogenital ridge are specific to the formation of the reproductive system :

A

●Paramesonephric ducts

●Genital ridge

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

In order for gonads to form, gonads need to be populated with?

A

Germ cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Cells that will produce sperm and locates are called?

A

Germ cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Germ cells migrate along the hindgut from the……. into…..

A

Posterior yolk sac

Dorsal mesentery

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Germ cells populate gonadal rudiments at?

A

5th week

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Germ cells populate the genital ridge at?

A

6th week

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Ternato a formation is due to?

A

Migration of germ cells to wrong place

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Lack of primordial germ cells (OGC) causes lack of?

A

Gonads

No PGC = no gonads

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

No gonads=

A

No development of the reproductive system

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Paramesonephric ducts form at time of?

A

Primordial germ cells (PGC) or Germ cell migration

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Paramesonephric ducts form by

A

Invagination of the urogenital ridge surface

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

In females invagination of paramesonephric ducts form?

A

Uterine tubes or degenerate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Degeneration or maintenance of paramesonephric ducts is dependent on hormonal influence

A

True or false

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Growth of irregular projections into mesenchyme of gonadal:
●Populated by PGCs
●Eventually differentiate into ova and sperm
●In all early embryos these cords are connected to the surface epithelium
●At this stage it is impossible to differentiate between the male & female gonad and the gonad is therefore known as the ?

A

INDIFFERENT GONAD

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What kind of gonads will develop depends on ?

A

Primary sex determination

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Whether we carry X and Y chromosomes or two X chromosomes usually determines?

A

Sexual phenotype

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

The male phenotype is usually associated with

A

XY

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

The female phenotype is usually associated with?

A

XX

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Which chromosome completes ovarian formation?

A

X

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Which chromosome drives Testes formation?

A

Y

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Development of one phenotype suppresses development of the other.

True or false?

A

True

Ie: get development of oocytes or sperm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

What does hypothesis I say determines sexual phenotype?

A

Presence of Y makes male

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

What does Hypothesis II say determines sexual phenotype?

A

No second X makes a male

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

Turner’s syndrome in gametes?

A

XO

Female

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

Trisomy X in gametes

A

XXX

Female

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

Kinefelter syndrome in gametes

A

XXY

Male

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

non -viable gametes

A

0Y

29
Q

XO in gametes is ?

A

Turner’s syndrome

Female

30
Q

XXX in gametes is?

A

Trisomy X

Female

31
Q

XYY in gametes is ?

A

Jacob’s or syndrome

Male

32
Q

Jacob’s syndrome in gametes is?

A

XYY

Male

33
Q

XXY in gametes is?

A

Kinefelter syndrome

Male

34
Q

XXYYin gametes is?

A

48 XXYY

Male

35
Q

XX in gametes is?

A

Normal female

36
Q

XY in gametes is?

A

Normal male

37
Q

What gene on Y chromosome codes for Testes determining factors (TDF) protein

A

SRY gene

38
Q

What is the crucial protein required for formation of the gonads?

A

SRY gene

39
Q

Gonads produce?

A

Hormones

40
Q

Which chromosome completes ovarian formation?

A

X

41
Q

Which chromosome drives Testes formation ?

A

Y

42
Q

Primary sex determination is?

A

Genetic: XX/XY

43
Q

Secondary sex determination is!

A

Development of sexual phenotype: external genitalia and internal reproductive structures

More hormonal than gene driven

44
Q

At 7 weeks, the genital tubercle in females is……. than in males.

This may lead to what?

A

BIGGER

Mistaken sex assignation in early prenatal scans

45
Q

The genital tubercle forms at?

A

4 weeks

46
Q

The anus is separate from the urogenital sinus at?

A

6 weeks

47
Q

In XX:
●Germ cells (oocytes) become surrounded by sex cord epithelia → follicles (granulosa cells).
●Oocytes are found around the periphery of the gonad. Ovarian tissue in the middle

AT WHAT WEEK?

A

Week 8

48
Q

In ovarian development the mesonephric tubule degenerates and become the ?

A

Epoophron and Paroophron

49
Q

At week 20 the paramesonephric (Müllerian ) duct remains and differentiates into?

A

Oviducts
Uterus
Vagina

50
Q

Lack of testosterone Leads to degeneration if which duct?

A

WolffIan (mesonephric) duct

51
Q

Lower part of paramesonephros fuse to form?

A

Uterus

52
Q

Presence of Oestrogen and absence of Testosterone causes the Müllerian ducts to form?

A

Uterus
Cervix
Upper vagina

53
Q

Presence of Oestrogen and absence of Testosterone causes the Genital tubercle to form?

A

Clitoris

54
Q

Presence of Oestrogen and absence of Testosterone causes the Labioscrotal folds to form?

A

Labia majora

55
Q

Oestrogen from the ovary means that you get internal development, so?

A

Paramesonephric[Mulleric )duct remains

56
Q

No testosterone, and presence of receptors for Oestrogen, means that you get

A

Clitoral and labial development

57
Q

Presence of a Y chromosome and the SRY gene leads to?

A

Gonadal development and external anatomy associated with male

58
Q

In XY at week 8

Mesodermal cells differentiate into?

A

Serotonin cells

59
Q

In XY at 16 weeks

Efferent ducts are remodelled from?

A

Kidney tubules

60
Q

At 16 weeks in CY

The mesonephric duct forms?

A

Epididymis and vas deferens

61
Q

Anti- mullerian hormone (AMH)causes in XY?

A

Degeneration of paramesonephric duct (muller Ian duct)

62
Q

Testosterone causes the WolffIan (mesonephric) ducts to become?

A

Epididymis
Vas deferens
Seminal vesicles

63
Q

DHT cause the Genital tubercle to become the?

A

Penis

64
Q

What causes the development of the penis from the genital tubercle?

A

DHT

65
Q

Blockage of Wnt suppression pathway allows growth of ?

A

External structures

66
Q

What is DHT

A

DHT=Dihydrotestosterone

Breakdown product of testosterone.

67
Q

Hormones in XY

A

Testosterone
AMH
DHT

68
Q

Testis descend out of abdomen, and back in through

A

Inguinal rings : pulled through by extension of gubernaculum

69
Q

What controls the descending of the testis?

A

Androgen and AMH

GU BLOCK (10 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions