Development of veins Flashcards
ولقد كنت في حلاوة طلبي العلم ألقى من الشدائد ما هو عندي أحلى من العسل لأجل ما أطلب وأرجو.
During the 5th week of development of the embryo enumerate the veins appear ?
1- Vitelline for the gut
2-umbilical connecting fetus to placenta
3-cardinal mean venous drainage of body
three end in sinus venosus
what does each vein drain ?
1-Vitlline
2-umbilical
3-cardina
1-vitlline : the gut and yolk sac retrun with poorly oxygeanted blood
2-umbilical : get the oxygenated blood from the cohrionic villi from the placenta
3-cardnal : drain the body wall return with poorly oxygenated blood
three drains into sinus venousu
وتارة يوقظني لقيام الليل ولذة مناجاتة، وتارة يحرمني ذلك مع سلامة بدني. ولولا بشارة العلم بأن هذانوع تهذيب وتأديب لخرجت إما إلى العجب عند العمل، وإما إلى اليأس عند البطالة.
Course of vitlline vein ?
pass through septum transversum to end in sinus venosus
كنت زمان الصبا آخذ معي أرغفة يابسة فأخرج في طلب الحديث، وأقعد على نهر عيسى فلا أقدر على أكلها إلا عند الماء. فكلما أكلت لقمة شربت عليها، وعين همتي لا ترى إلا لذة تحصيل العلم.
What happenes to vitlline vein caudal to septum transversum ?>
the two branches of vitltine anastomose together by 3channels 2 ant and one post to the future forming duodenum and formin 8 shape
then the 8 disappear leaving the Portal vein and its left and right tributaries ?
Spleinc vein and superior mesenteric vein draining the gut
فأثمر ذلك عندي أني عرفت بكثرة سماعي لحديث الرسول ﷺ وأحواله وآدابه، وأحوال أصحابه وتابعيهم، فصرت في معرفة طريقه كابن أجود.
Show portal vein formation ?
caudally to septum transversum ,
the two branches of vitltine anastomose together by 3channels 2 ant and one post to the future forming duodenum and formin 8 shape
then the 8 disappear leaving the Portal vein and its left and right tributaries ?
Spleinc vein and superior mesenteric vein draining the gut
وأثمر ذلك عندي من المعاملة ما لا يدري بالعلم، حتى أنني أذكر في زمان الصبوة ووقت الغلمة والعزبة قدرتي على أشياء كانت النفس تتوق إليها توقان العطشان إلى الماء الزلال، ولم يمنعني عنها إلا ما أثمر عندي العلم من خوف الله عز وجل. ولولا خطايا لا يخلو منها البشر، لقد كنت أخاف على نفسي من العجب.
show formation of splenic vein?
show formation of Suprior Mesenteric vein ?
the two branches of vitltine anastomose together by 3channels 2 ant and one post to the future forming duodenum and formin 8 shape
then the 8 disappear leaving the Portal vein and its left and right tributaries ?
Spleinc vein and superior mesenteric vein draining the gut
What happens to vitlline vein inside septum transversm?
They are interrupted by the growing hepatic cords forming hepatic siusoids
غير أنه عز وجل صانني، وعلمني، وأطلعني من أسرار العلم على معرفة، وإيثار الخلوة به، حتى إنه لو حضر معي معروف وبشر لرأيتهما زحمة.
Show formation of sinusoids
vitlline vein inside septum transversm
They are interrupted by the growing hepatic cords forming hepatic siusoids
What happens to the vitlline veins between the septum transversum and sinus venosus?
they from right and left hepatic veins forming the common hepatic vein
forms the hepatic segment of IVC which drains into RA
ثم عاد فغمسني في التقصير والتفريط حتى رأيت أقل الناس خيرا مني.
Show formation of Common hepatic vein
vitlline veins between the septum transversum and sinus venosus
they from right and left hepatic veins forming the common hepatic vein
لكن رجائي في فضله قد عادل خوفي منه. وقد يغلب الرجاء بقوة أسبابه، لأني رأيت أنه قد رباني منذ كنت طفلا
Does vitlline vine paly a role in forming IVC ?
vitlline veins between the septum transversum and sinus venosus
forms the hepatic segment of IVC which drains into RA
Umbilical vein which diappear
Right umbilical vein
الطيبين بيمشوا بدري
Why umbilical vein lose their connetion with heat ?
Because of liver enlargement so it drains into liver
what does umbilical vein do caudal to septum transversum ?
it connects the placenta to the left branch of portal vein آسف
What is the fate of the part of umbilical vein inside the septum transversum?
it connects with liver siusoids
forming ductus venosus between the left umbilical and common hepatic
the part of umbilical vein between septum transversum and sinus venosus fate what is it ?
Disappear !
The fate of
Left umbilical vein is ?
Ductus venosus is ?
Left umbilical vein is obliterated forming ligamentum teres
Ductus venosus if obliterated forming ligamentum venosum
obliterated forming ligamentum teres
The fate of
Left umbilical vein is
واتقون يا أولي الألباب
دع ما يريبك إلي ما لا يريبك !
لو كنت متوضا وصليت ولا تتذكر هل انتقض الوضوء ام لا
انت تعلم انك كنت متوضا هذا لاريب فيه ولكن الشك في الانتقاض اذن الصلاة صحيحة دع الشك
اذا كثر الوسواس فلا عبرة به
Cardinal vein drain ?
formed ?
main venous drainage of the body
is formed by union of anterior cardiac vein draining cephalic part of body
and posterior cardiac vein draining the caudal part
Other name of Common cardinal vein is ?
What is their fate
Ductus of cuvir
Left common cardianl > oblique vein of left atrium opein into coronary sinus
Right common cardinal >lower part os superior vena cava below azygous@@ important
Left common cardianl fate ?
Left common cardianl > oblique vein of left atrium
Right common cardinal fate ?@@ important
> lower part os superior vena cava below azygous
ولا يصدنك عن آيات الله بعد إذا أنزلت إليك
وادع إلي ربك
Whate are anterior cardiac vein
2 veins are conneted together by oblique anstomosis making blood run from left to right
The right anterior cardinal vein fate?
SVCA IINTO?
upper part of superior vena cave
Right innominate vein
Right internal jugular vein IJV
The left anterior cardinal vein fate ?
Left internal juglar vein
Left superior intercoastal vein
into inte ?
The left anterior cardinal vein fate ?
The left anterior cardinal vein fate ?
Left internal juglar vein
Left superior intercoastal vein
into inte ? after losing anastomisng with right anterior cardinal vein
The right and lef innominate origin ?
Right innominate : right anterior cardinal vein
left innmoinate : oblique anastomosis
Subclavian vein ,
how is it formed?>
where it ends?
Its formed by the venous pleuxes of the upper limb
it ends in the anterior cardinal vein
What about external jugular vein???<
,
From the veins at the mandibular region of embryo forming External jugular vein
SO the formation of svc by ?
The lower part of svc below azygous by the right common cardinal
the upper part of svc by the proximal ! right anterior cadianal vein
Ant upper alphapetical order
The posterior caridnal veins anatomse or no ?
they have iliac anastomsis
The posterior cardinal veins are replaced by?
the supracardinal vein
the subcardinal vein
the remenats of posteriros cardinal veins
2 common iliac + Root of azygous
the right posteor cardinal
right common iliac and root of azygous
the left posteror cardinal
lef common iliac
The subcarinal and supracardinal anastomosis
The blood run from left to right by the transverse channels connecting :
2 supracardinals
2 subcardina
suprasubcardinal
The subcardinal fate ?
it drains kidenys supra renals and gonads
giving on both sides
suprarenal vein
gonadal vein
on the right side MOST OF IVC !
forming subcardinal segement of IVC
froming hepatic suncardinal segment of IVC
the Supracardinal anastomsis fom>
the connection between azygous and hemiazygous
The anastomsis betwwen 2 sub cardinals ?>K
aleft left part of Renal vein
The supra-sub cardinal anastomsis form
Part of renal vein on both sides
right side form part of IVC
Mention supracardinal vein fate .
Cranial-caudal
cranial right azygous left hemi azygous caudal called sacrocardinal right IVC LEFT disappear
the anastomosis between both gives connection between azyougs and hemi
Vitelline vein and IVC?
Rt . Vitelline vein form the common hepatic vein which forms hepatic segment of IVC
Right subcardinal role in formation IVC ?>
shares in 2 segemets of IVC
gives the subcardinal vein !
share in hepatic subcardinal segement by its connection with common hepatic vein
Hepatic subcardinal segment OF IVC ARISE FROM
Connection of the RT.subcardinal vein With common hepatic vein
The subcardinal-supracardinal segment of the IVC
From the subcardinal supracardinal anastomisis
Supracardinal segment of IVC?
From the caudal part of Rt supracardinal vein
The formation of IVC
Hepatic subcardinal hepatic subcardinal subsupracardinal suprecardinal
It is formed by 5 segments !
Hepatic segemrnt : the right terminal of vitlline vein give common hepatic which form the hepatic segments
subcardinal hepatic segments: connection of common hepatic and right subcardinal vein
subcardinal segment : from right subcardinal vein
supre-subcardinal segments : anastomisis betweein sub and supra cardinal
supra cardinal segments caudal of Rt .supracardinal vein
SVC anomalies
Mention
1-double svc when there is riht one open diectly in right atrium
and left one opens into enlarged coronary sinus in dierctly to the right atrium
2-left svc only as mentioned above withouth the right one
Anomalies if IVC?>o
1-Double IVC
2- ABSENT IVC why:”?
drains into azygous into SVC into RA
MCQ 1-the oblique vein formed from ?> 2-the upper svc from 3-left brachiceoalic arise from 4-ductus venosus is betweem ?
1-left common cardinal
2-right anterior cardinal
3-anastomisis between two ant cardianl
4-left umbilical vein and the common hepatic vein
Mention Hydralazine and Na nitroprusside as vasodilators mechanism of action
Hydralazine :Arteriolar dilator: K+
channel opener
→ hyperpolarization → ↓ Ca++ influx
into vessel wall
Na nitroprusside : Mixed dilator: Nitric oxide donor → ↑cGMP → ↓Ca++ influx into vessel wall. Do
not need SH group (no tolerance, unlike Nitrates
Cholesterol (27C), very hydrophobic
• 4 fused hydrocarbon rings
• (A, B, C, and D “steroid nucleus”),
8 C, branched hydrocarbon chain attached to C-17 of the D ring.
• Ring A has OH at C-3, and ring B has a double bond between C5 &
C6.
• Most plasma cholesterol is in an esterified form (with a fatty acid attached at carbon 3), which makes the structure even more hydrophobic than free(unesterified) cholesterol. • Cholesteryl esters are not found in membranes, and are normally present only in low levels in most cells.
• Because of their hydrophobicity, cholesterol and its esters must be transported how ? in association with protein as a component of a lipoprotein particle (explained later) or be solubilized by phospholipids and bile salts in the bile
in association with protein as a component of a lipoprotein particle or
be solubilized by phospholipids and bile salts in the bile
Importance of Cholesterol
•Structural component of cell membranes •It is a precursor of important compounds: corticosteroids bile acids sex hormone vit D
Cholesterol travels in the blood
transported in molecules called lipoproteins.
• These are sphere shaped assemblies
(containing lipids and proteins) that keep
• the cholesterol separated from the blood.
• The molecules have specific receptors that direct them to certain
tissues in the body
- HDL transport cholesterol
* LDLtransport cholesterol
from body tissues to the liver.
from the liver to the cells of the body
Double SVC due to
?
failure of formation of cranial anastomsis
Left svc due to ?
reversal of shunt
Double IVC due to ?
Lost iliac anastomisis
persistant caudal of left supracardinal
the left common iliac doesn’t joint the right but conitnues as left ivc opening in left renal vein
Absent IVC due to ?
Failure of the subcardinal to anastomise with common hepatic but instead with the supra cardinal s o
IVC drains into the Azygous then SVC RA
