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Development of the eye Flashcards

1
Q

The Ectoderm of the eye gives rise to what?

A
  • Lens
  • Part of the Cornea

portion of The eyelids

eyelashes and glands in the eyelids

the lacrimal glands

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2
Q

The neuroectoderm forms the

A
  • Retina
  • Pigmented epithelium of the Irirs
  • Optic Nerve
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3
Q

Mesoderm Forms what in the eye?

A

Cornia Angioblasts of the Chorioid Layer

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4
Q

Neural crest cells migrate into the mesenchyme from the neural crest and differentiate into

A

choroid

and

sclera part of the cornea (corneal endothelium)

The chorid is the innder vascularized layer under the scalera

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5
Q

When does eye development begin?

A

The Start of the 4th week

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6
Q

What is the initial events of formation of the eye

A

Optic Groove

Optic Vesicle

Optic Stalk

GVS

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7
Q

Anophotalmia

A

Optic Vesicle does not form correctly.

Lack of eyes

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8
Q

What is the primordia of the lenses?

A

Lense Placodes Lense Pits Lense Vesicles (PPV)

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9
Q

How are Optic Cups formed

A

The Optic Vesicle invaginates to form a “CUP”

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10
Q

What are “Linear grooves - retinal fissures”

A

Form in the Optic Stalk Future site of the Centeral Artery and Vessel of the retina

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11
Q

When is the Optic Stock Lumen obliterated to become the Optic Nerve?

A

Week 8

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12
Q

What is COLOCBOMA

A

A defect in the eye Caused by incomplete closure of the Retinal Fissures during week 6 Autosomal Dominate

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13
Q

primary vitreous body Where is it found?

A

Between the Optic Cup and the Lens Vesicle.

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14
Q

primary vitreous body What does it do?

A

Lubricates and provides nutrients to the Lens Called Vitreous Humor

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15
Q

What is the pupillary membrane?

A

Branches of the Hyaloid artery called the Tunica Vasculosa Lentis. The Pupillary Membrane is the most anterior portion of this structure.

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16
Q

The pupil forms before/after the degradation of the pupillary membrane?

A

After the degradation of the membrane

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17
Q

What is persistent pupillary membrane?

A

When the pupillary membrane does not completely disintegrate.

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18
Q

What is the cause of congenital cataracts?

A

The most common causes are

  • Trisomy 21
  • Maternal Diabetes
  • Rubella
  • Galactosemia
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19
Q

What are the two layers of the retina?

A

The thick inner layer - holds the nerves for vision The thin outer layer - pigmentation of the retina.

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20
Q

What are the two layers of the retina separated by?

A

Intraretinal Space

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21
Q

When does the intraretinal space disappear?

A

by the 7th week.

(space between the thick and thin membrane)

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22
Q

What is caused by a blow to the eye or head?

A

Retinal detachment.

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23
Q

What is the light sensitive part of the retina?

A

The thick inner layer. - becomes the neural retina

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24
Q

What does the neuro retinal contain?

A

Rods and cones, Cell bodies of neurons

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25
Q

What does the thin-outer wall become?

A

cuboidal melanin-containing pigmented epithelium.

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26
Q

myelination of the eye nerve takes place when?

A

After 10-12 weeks of light exposure.

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27
Q

The mesenchyme (nuero crest orgin) surrounding the optic cup differentiates into what?

A

inner vascular layer- the choroid

outer fibrous layer - the sclera

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28
Q

What is the ciliary body?

A

Wedged shape extention of the Choroid.

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29
Q

What function does the ciliary body have?

A

Ciliary Muscle - focusing the lens

Ciliary Process - producing aqueous humor

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30
Q

Dranage of the Aqueous Humor is done by the

A

trabecular Meshwork - Venus drainage

and

Canal of schlemm-

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31
Q

Congenital Glaucoma

A

Over production of the aqueous Humor ( Ciliary Process)

Under drainage problem (Trabecular Meshwork or Canal of Schlemm.

Can also be caused by Rubella during pregnancy.

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32
Q

The iris is derived from what structure?

A

The Optic Cup. Both Layers Thick inner and Thin outer

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33
Q

Connective tissue of the iris is derived from what/

A

Neurocrest cells

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34
Q

The dilator pupillae is derived from what?

A

neuroectoderm of the optic cup.

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35
Q

What innervates the dilator Pupillae?

A

Sympathetic nerves from the Superior cervical Ganglion

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36
Q

What innervates the sphincter pupillae

A

Parasympathetic nerves from Edinger Weshphal

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37
Q

Eye color is determined by ?

A

The level of pigment in each layer in the iris Posterior only - blue throughout Iris - brown

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38
Q

Cornia formation is induced by what?

A

The Lens Vesicle.

39
Q

What three sources make up the cornia

A
  • Ecoderm,
  • Mesoderm
  • Nurocrest cells
40
Q

When do the eyelids develop?

A

During the 6th week

41
Q

What makes up the eye lids

A
  • neural crest cell
  • mesenchyme
  • Cutanious folds of ectoderm.
42
Q

What is forming during the 26-28 weeks as the eyes are opening?

A

bulbar conjunctiva and palpebral conjunctiva

43
Q

eyelashes and glands in the eyelids are derived from what?

A

surface ectoderm.

44
Q

When do the eyes start to open

A

Week 26-28

45
Q

lacrimal glands develop from

A

surface ectoderm

46
Q

solid buds from the surface ectoderm canalize to form

A

nasolacrimal ducts

47
Q

Symptoms of retinal detachment

A

Phototobia - flashes of light Myopia

48
Q

Lens Part of the Cornea

A

The Ectoderm of the eye gives rise to what?

49
Q

Retina Pigmented epithelium of the Irirs Optic Nerve

A

The neuroectoderm forms the

50
Q

Cornia Angioblasts of the Chorioid Layer

A

Mesoderm Forms what in the eye?

51
Q

choroid sclera part of the cornea (corneal endothelium)

A

Neural crest cells migrate into the mesenchyme from the neural crest and differentiate into

52
Q

The Start of the 4th week

A

When does eye development begin?

53
Q

Optic Groove Optic Vesicle Optic Stalk

A

What is the initial events of formation of the eye

54
Q

Optic Vesicle does not form correctly.

A

Anophotalmia

55
Q

Lense Placodes Lense Pits Lense Vesicles (PPV)

A

What is the primordia of the lenses?

56
Q

The Optic Vesicle invaginates to form a “CUP”

A

How are Optic Cups formed

57
Q

Form in the Optic Stalk Future site of the Centeral Artery and Vessel of the retina

A

What are “Linear grooves - retinal fissures”

58
Q

Week 8

A

When is the Optic Stock Lumen obliterated to become the Optic Nerve?

59
Q

A defect in the eye Caused by incomplete closure of the Retinal Fissures during week 6 Autosomal Dominate

A

What is COLOCBOMA

60
Q

Between the Optic Cup and the Lens Vesicle.

A

primary vitreous body Where is it found?

61
Q

Lubricates and provides nutrients to the Lens Called Vitreous Humor

A

primary vitreous body What does it do?

62
Q

Branches of the Hyaloid artery called the Tunica Vasculosa Lentis. The Pupillary Membrane is the most anterior portion of this structure.

A

What is the pupillary membrane?

63
Q

After the degradation of the membrane

A

The pupil forms before/after the degradation of the pupillary membrane?

64
Q

When the pupillary membrane does not completely disintegrate.

A

What is persistent pupillary membrane?

65
Q

The most common causes are Trisomy 21 Maternal Diabetes Rubella Galactosemia

A

What is the cause of congenital cataracts?

66
Q

The thick inner layer - holds the nerves for vision The thin outer layer - pigmentation of the retina.

A

What are the two layers of the retina?

67
Q

Intraretinal Space

A

What are the two layers of the retina separated by?

68
Q

by the 7th week.

A

When does the intraretinal space disappear?

69
Q

Retinal detachment.

A

What is caused by a blow to the eye or head?

70
Q

The thick inner layer. - becomes the neural retina

A

What is the light sensitive part of the retina?

71
Q

Rods and cones, Cell bodies of neurons

A

What does the neuro retinal contain?

72
Q

cuboidal melanin-containing pigmented epithelium.

A

What does the thin-outer wall become?

73
Q

After 10-12 weeks of light exposure.

A

myelination of the eye nerve takes place when

74
Q

inner vascular layer- the choroid outer fibrous layer - the sclera

A

The mesenchyme surrounding the optic cup differentiates into what?

75
Q

Wedged shape extention of the Choroid.

A

What is the ciliary body?

76
Q

Ciliary Muscle - focusing the lens Ciliary Process - producing aqueous humor

A

What function does the ciliary body have?

77
Q

trabecular Meshwork - Venus drainage Canal of schlemm-

A

Dranage of the Aqueous Humor is done by the

78
Q

Over production of the aqueous Humor ( Ciliary Process) Under drainage problem (Trabecular Meshwork or Canal of Schlemm. Can also be caused by Rubella during pregnancy.

A

Congenital Glaucoma

79
Q

The Optic Cup. Both Layers Thick inner and Thin outer

A

The iris is derived from what structure?

80
Q

Neurocrest cells

A

Connective tissue of the iris is derived from what/

81
Q

neuroectoderm of the optic cup.

A

The dilator pupillae is derived from what?

82
Q

Sympathetic nerves from the Superior cervical Ganglion

A

What innervates the dilator Pupillae?

83
Q

Parasympathetic nerves from Edinger Weshphal

A

What innervates the sphincter pupillae

84
Q

The level of pigment in each layer in the iris Posterior only - blue throughout Iris - brown

A

Eye color is determined by ?

85
Q

The Lens Vesicle.

A

Cornia formation is induced by what?

86
Q

Ecoderm, Mesoderm Nurocrest cells

A

What three sources make up the cornia

87
Q

During the 6th week

A

When do the eyelids develop?

88
Q

neural crest cell mesenchyme Cutanious folds of ectoderm.

A

What makes up the eye lids

89
Q

bulbar conjunctiva and palpebral conjunctiva

A

What is forming during the 26-28 weeks as the eyes are opening?

90
Q

surface ectoderm.

A

eyelashes and glands in the eyelids are derived from what?

91
Q

Week 26-28

A

When do the eyes start to open

92
Q

surface ectoderm

A

lacrimal glands develop from

93
Q

nasolacrimal ducts

A

solid buds from the surface ectoderm canalize to form

94
Q

Phototobia - flashes of light Myopia

A

Symptoms of retinal detachment

Nuro (9 decks)

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