Development of the digestive system Flashcards

1
Q

What occurs during week one of development?

A

Fertilisation to implantation

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2
Q

What forms in week 2 of development?

A

Bilaminar Germ Disk

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3
Q

What occurs in week 3 of development?

A

Trilaminar Germ Disc forms

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4
Q

What occurs in weeks 3-8 of development?

A

Organogenesis

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5
Q

What is the first phase of embryonic development?

A

Growth phase - cells divide

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6
Q

What is the second phase of embryonic development?

A

Morphogenesis - development of shape, size of organs

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7
Q

What is the third phase of embryonic development ?

A

Differentiation - Maturation of physiological processes

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8
Q

What does the ectoderm form?

A

Skin, CNS, PNS, liver, eyes, nose, ears

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9
Q

What does the endoderm form?

A

Epithelial lining of resp. system, GIT, Liver,pancreas, thyroid, bladder etc

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10
Q

What does the mesoderm?

A

Muscle, bones, cartilage, dermis, vascular system, urogenital system, spleen etc

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11
Q

The lateral plate mesoderm gives rise to what?

A

Parietal and visceral mesoderm

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12
Q

Where does the foregut arise from?

A

The cranial part of the primitive gut tube

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13
Q

What divides the foregut into trachea and oesophagus?

A

Tracheo-oesophageal septum

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14
Q

When does the foregut dilate to form the stomach?

A

Week 4

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15
Q

How is the stomach attached to the dorsal and ventral wall?

A

Via a mesentery called the mesogastrium

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16
Q

How is the duodenum formed?

A

From the caudal part of the foregut and the cranial part of the midgut

17
Q

What supplies the duodenum?

A

The coeliac trunk and the superior mesenteric artery

18
Q

When does the liver bud appear?

A

Third week

19
Q

When does the spleen form

A

END OF WEEK 4/ START OF WEEK 5

20
Q

What occurs if the tracheo-oesophageal septum deviates incorrectly?

A

Atresia and tracheo-oesophageal fistula

21
Q

What occurs if the ventral bud fails to deviate around the duodenum correctly?

A

Annular pancreas which may result in duodenal stenosis

22
Q

What does the midgut form?

A

The distal part of the duodenum, jejunum, ileium, caecum, appendix, ascending colon and proximal 2/3 of transverse colon

23
Q

What does the cephalic part of the primary intestinal loop form?

A

The distal duodenum, jejunum and the proximal ileum

24
Q

What does the caudal part of the distal ileum become?

A

Distal ileum, appendix, ascending colon and proximal 2/3 of the transverse colon

25
Q

When does midgut rotation occur?

A

Week 6

26
Q

What is omphalocele and how does it occur?

A

The herniation of abdominal viscera through an enlarged umbilical ring as a result of the failure of retraction of umblilical ring

27
Q

What happens if there are remnants of the vitelline duct?

A

Meckels diverticulum which may form fistula or cyst

28
Q

What does the hindgut form?

A

Distal 1/3 of transverse colon, descending colon, sigmoid colon, rectum and upper part of anal canal

29
Q

What does the endoderm of the hindgut form?

A

the lining of the bladder and urethra

30
Q

What supplies the hindgut?

A

The inferior mesenteric artery

31
Q

When does the liver form?

A

Week 3

32
Q

What is gastrochisis?

A

Herniation of abdo viscera. No amnion covering viscera

33
Q

What layer makes the spleen?

A

Mesoderm

34
Q

When does midgut rotation occur?

A

Week 6