Development of Nervous System Flashcards
Neurulation
formation of the neural tube
when does neurulation take place
22-23 days
neural crest formation
neuroectodermal cells at the crests detach to form the neural crest
where do neural crest cells migrate to
pharyngeal arches, ganglia, neuroglia, adrenal medulla, melanocytes
when do neurons form
between 4-20 weeks
what do neurons form
processes, and establish synaptic contacts
when do glioblasts appear and where
in ventricular zone at 19 weeks
what do glioblasts develop into
ependymocytes, astrocyte, oligodendrocyte
what are microglia derived from
hemopoietic cells that migrate to the CNS late in teh fetal period
what does prosencephalon give rise
telencephalon and diencephalon
what is the derivative of the forebrain
prosencephalon
what is the derivative of the midbrain
mesencephalon
what is the derivative of teh hindbrain
rhombencephalon
what does rhombencephalon give rise to
metencephalon, myelencephalon
what does metencephalon give rise to
pons, cerebellum, upper 4th ventricle
what does myelecephalon give rise to
medulla, lower 4th ventricle
where is cephalic flexure found
at mesencephalon
where is pontine flexure found
between mesencephalon and myelencephalon
where is cervical flexure found
between rhombencephalon and spinal cord
what are oligodendrocytes derived from
neuroepithelial cells of CNS
what are schwann cells derived from
migrating neural crest cells
occulta spina bifida
incomplete closure of bony spinal column, usually no apparent damage to spinal cord - mild form
spina bifida cystica with meningocele
meninges and portion of spinal cord and nerved protrude through teh bertebral cleft
what are some other symptoms of spina bifida cystica with meningocele
hydrocephalus, muscle weakness, loss of senestation
