Development of Head and Neck Flashcards
Treacher-Collins Syndrome
- etiology
- presentation
- neural crest cell migration failure
- abnormal 1st arch derivatives, conductive hearing loss
Pierre-Robin Syndrome
- etiology
- presentation
- neural crest cell migration failure
- U-shaped cleft soft palate –> suckling difficulties
Which nerve is derived from the first arch?
trigeminal
Meckel’s cartilage
- derived from
- becomes
- 1st arch
- core of mandible
Goldenhar Syndrome
- arch(es)
- presentation
- 1st and 2nd
- malformed face, usually unilateral
Which nerve is derived from the second arch?
facial
Stylohyoid is innervated by which nerve?
facial
Where are the thyroid and cricoid cartilages derived from?
4th and 6th arches
4th arch nerve
superior laryngeal
6th arch nerve
recurrent laryngeal
Auditory tube, middle ear cavity, mastoid air cells
1st pharyngeal pouch derivatives
Palatine tonsils
2nd pharyngeal pouch derivatives
Thymus and inferior parathyroid glands
3rd pharyngeal pouch derivatives
Superior parathyroid glands and ultimobranchial bodies
4th pharyngeal pouch derivatives
DiGeorge Syndrome
- etiology
- presenation
-neural crest cell migration failure
=>3rd and 4th pouch failure (parathyroid and thymus absence)
=>1st arch malformation
-hypocalcemia + facial deformaties
1st pharyngeal membrane persists as
tympanic membrane
1st pharyngeal cleft persists as
epithelial lining of external auditory meatus
Branchial cysts
surrounded by tissue on both sides
Branchial sinus
open on one side
Branchial fistulae
open on both sides–essentially tube
Lateral cervical cyst
lateral neck mass, failure of 2nd arch closure
Thyroglossal duct cyst
midline, normally connects tongue to thyroid
First treatment of thyroglossal duct cyst?
treat infection first
Lingual thyroid
failure of thyroid to migrate inferiorly
Ankyloglossia
tongue-tied
Pituitary layer derivation
evagination of endothelium
Neck mass is adult
cancer until you prove it otherwise
