Development and Organisation of the Alimentary System, Liver & Pancreas Flashcards

1
Q

Accessory Organs of the gut

A
  • salivary glands
  • liver & gall bladders
  • pancreas
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2
Q

Where do mouth parts develop from?

A

branchial arches

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3
Q

Where (other than the mouth) forms from the branchial arches?

A
  • ear
  • hand
  • neck
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4
Q

Describe mesoderm

A
  • middle developmental layer between the ectoderm and endoderm
  • gives rise to the skeleton, muscle, heart and bones
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5
Q

What are indents in the branchial arches known as?

A

pharyngeal clefts or grooves

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6
Q

What are supplied by a cranial nerve in branchial arches?

A

cartilage and muscular components

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7
Q

How many pharyngeal arches are there in branchial arches?

A

6

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8
Q

How many clefts are there in branchial arches?

A

4

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9
Q

What develops from the first branchial arch?

A
  1. skin of jaw
  2. salivary glands
  3. tooth enamel
  4. buccal cavity
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10
Q

What develops from the 1st cleft of branchial arches?

A
  • external components of middle ear
  • tympanum
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11
Q

What develops from the 1st pouch of branchial arches?

A

auditory tube

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12
Q

What develops from the 2nd, 3rd and 4th branchial arches?

A

skin of the ear & neck

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13
Q

What develops from the 2nd pouch of branchial arches?

A

tonsils & lymphatics

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14
Q

What develops from the 3rd pouch of branchial arches?

A

thymus & thyroid

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15
Q

What develops from the 4th pouch of branchial arches?

A

thyroid

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16
Q

What 3 “parts” are in each branchial arches?

A
  1. nerves
  2. arteries
  3. cartilage
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17
Q

What does the gut develop as?

A

an endodermal tube

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18
Q

What surrounds the endoderm?

A

Splanchnic mesoderm

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19
Q

What forms muscle & connective tissue?

A

Splanchnic mesoderm

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20
Q

What provides nutrients to the embryo as the placental plate develops?

A

a yolk sac

21
Q

At what week of embryo development do accessory organs appear?

A

week 6

22
Q

What are the 4 layers of the gut wall?

A
  1. mucosa
  2. submucosa
  3. muscularis externa
  4. serosa
23
Q

Describe mucosa

A
  • lines the gut lumen
  • has 3 layers
  • has a thin ring of longitudinal smooth muscle
  • contains mucus and electrolyte-secreting glands
    -surface normally highly folded to increase digestive surface area
24
Q

Describe submucosa

A
  • thick layer of connective tissue
  • provides structural support and elasticity
  • contains submucosal nerve network
25
Q

Describe muscularis externa

A
  • has inner ring of circular smooth muscle
  • has outer ring of longitudinal muscle
  • contracts tube diameter
  • constricts gut length
26
Q

Describe serosa

A
  • outer connective tissue layer
  • secretes fluid to lubricate organs of the coelom
  • attached to mesenteric membranes
27
Q

What is the primary region of nutrient absorption?

A

the small intestine

28
Q

What increases the absorptive area in the small intestine?

A

circular folds, villi, and microvilli

29
Q

What are villus lined with?

A

epithelial cells and mucus-secreting cells

30
Q

What is contained within villus?

A
  • an arterial and venous circulation
  • a lymphatic vessel
31
Q

What is the lymphatic system prominent in?

A

lipid absorption

32
Q

Describe the crypt of lieberkuhn

A
  • site of enterocyte
  • a site of water and mucus secretion
33
Q

What is the primary function of the large intestine

A

water re-absorption and drying of feces

34
Q

Where does the liver develop from?

A

ventral hepatic bud from foregut endoderm

35
Q

What is the liver organized into?

A

units called lobules

36
Q

What is each lobule in the liver fed by a branch of?

A

the hepatic artery and the portal vein

37
Q

Where is bile stored?

A

the gall bladder

38
Q

What is a sinusoid?

A

blood from the hepatic artery and portal vein that flows into the same capillary vasculature

39
Q

Where does the alimentary tube develop from?

A

the cephalic and caudal parts of the embryo

40
Q

Where does the pancreas develop from?

A

dorsal & ventral pancreatic buds

41
Q

What is the pancreas organized into?

A

exocrine and endocrine structures

42
Q

How is the exocrine pancreas organized?

A

as a series of glands along the pancreatic duct which drains into the duodenum

43
Q

Describe duct cells in the exocrine pancreas

A
  • exist at the base of each gland
  • secrete bicarbonate
  • the bicarbonate neutralizes digestive juices from the stomach
44
Q

Describe acinar cells in the exocrine pancreas

A
  • at the head of each gland
  • secrete digestive enzymes into the duct
45
Q

Where does the exocrine pancreas develop from?

A

the ventral pancreatic bud

46
Q

Where does the endocrine pancreas develop from?

A

the dorsal pancreatic bud

47
Q

What are islets of Langerhans in the endocrine pancreas?

A

a series of secretory islets perfused by a capillary network

48
Q

What do islet cells do?

A

secrete metabolic hormones (insulin, glucagon and somatostatin)

49
Q
A