Dermatology COPY Flashcards
Define Macule
Non palpable
Well circumscribed change in skin color
Less than 1 cm
What is the primary morphology of this lesion?
Macule
(labial melanotic macule)
Define Patch
nonpalpable
well circumscribed change in skin color
Larger than 1 cm
What is the primary morphology of this lesion?
Patch
(Speckled Nevus)
Define Plaque
Palpable
Elevated
Solid skin lesion
Greater than 1 cm
Define Papule
Palpable
Elevated
Solid skin lesion
Less than 1 cm
What is the primary morphology of this lesion?
Papule
(Spitz nevus)
What is the primary morphology of this lesion?
Plaque
(Psoriatic plaque)
Define Wheal
Transient
Smooth papule or plaque
Seen in urticaria
What is the primary morphology of this lesion?
Wheal
(Urticaria)
Define Vesicle
Small
Fluid containing blister
Less than 1 cm
What is the primary morphology of this lesion?
Vesicles
(Herpes Zoster)
Define Bulla
Large
Fluid containing blister
Greater than 1 cm
Define Pustule
Vesicle containing pus
Define Nodule
Solid
Non-superficial skin mass
1-2 cm
Define Tumor
Solid skin mass
Greater than 2 cm
What is the primary morphology of this lesion?
Bulla
(Bullous Pemphigoid)
What is the primary morphology of this lesion?
Pustules
(Pustular psoriasis)
What is the primary morphology of this lesion?
Nodule
(Large pigmented dermatofibroma)
What is the primary morphology of this lesion?
Tumor
(Melanoma)
Define Scale
Flaking off of the stratum corneum
Define Crust
Dried exudate
Define Excoriation
Linear skin damage
Due to scratching or scraping
Define Lichenification
Skin thickening
Prominent skin lines
Due to repeated rubbing or scratching
Define Erosions
Loss of areas of the epidermis
Due to:
- Manipulatin of the skin
- Popping blistered areas
Define Ulcers
Deep areas of skin loss
Extends at least into the deeper dermis
Define Fissures
Cracking of the skin
Somewhat linear pattern
Define Atrophy
Thinning of the skin
Define Hypertrophy
Thickening of the skin
What is the secondary morphology of this lesion?
Scale
(Scalp psoriasis)
What is the secondary morphology of this lesion?
Crust
(Superficial infected atopic dermatitis)
What is the secondary morphology of this lesion?
Excoriations
(Scratching due to psoriasis)
What is the secondary morphology of this lesion?
Lichenification
(Lichen simplex chronicus)
What is the secondary morphology of this lesion?
Erosions
(Bullous pemphigoid after blisters have broken)
What is the secondary morphology of this lesion?
Ulcer
(Venous stasis ulcer)
What is the secondary morphology of this lesion?
Fissures
(Hand dermatitis)
What is the secondary morphology of this lesion?
Atrophy
(Discoid lupus)
What is the secondary morphology of this lesion?
Hypertrophy
(Hypertrophic lichen planus)
Define Erythematous
Pink to red
Increase in blood flow to the area
Define hypopigmented
Decrease in pigmentation from the surrounding area
Define Depigmented
Complete lack of pigmentation
Define Hyperpigmented
Increase in pigmentation from the surrounding skin
What is color/pigmentation of this lesion?
Erythematous
(Erythrodermic psoriasis)
What is color/pigmentation of this lesion?
Hypopigmented
(Postinflammatory hypopigmentation with treatment of psoriasis)
What is color/pigmentation of this lesion?
Depigmented
(Vitiligo)
What is color/pigmentation of this lesion?
Hyperpigmented
(Postinflammatory hyperpigmentation and Acanthosis nigricans)
Define Ecchymosis
Bruising from bleeding under the skin
Define Petechiae
Pinpoint bleeding in the skin
Define Purpura
Larger areas of bleeding or vascular inflammation
Define Telangiectasis
Small dilated vessels
Define Nummular
Coin shaped
Define Serpiginous
Snakelike 🐍
Define Annular
Bordered by a raised ring
Define Reticular
Netlike
Define Umbilicated
Like an umbilicus
Describe the distribution of Acral
Hands and Feet
Describe the distribution of Intertriginous
In areas of skin folds
Describe the distribution of Photo-distributed
In areas prone to sun exposure
Define Verrucous
Wartlike with a rough surface
What vascular term would be used to describe this lesion?
Petechiae
(Thrombocytopenia)
What vascular term would be used to describe this lesion?
Purpura
(Palpable Purpura in Henoch-Schonlein purpura)
What vascular term would be used to describe this lesion?
Telangiectasias
(Rosacea)
Describe the surface characteristics of this lesion
Verrucous
(Wart)
Describe the surface characteristics of this lesion
Pearly and smooth
(Basal Cell Carcinoma)
Describe the shape of this lesion
Nummular
(Nummular Dermatitis)
Describe the shape of this lesion
Serpiginous
(Cutaneous larva migrans)
Describe the shape of this lesion
Annular
(Granuloma annulare)
Describe the shape of this lesion
Reticular
(Livedo Reticularis)
Describe the shape of this lesion
Umbilicated
(Molluscum)
How would you describe the location of this condition?
Intertriginous
(Inverse psoriasis)
Differential diagnosis for skin lesion with plaques and scales?
Psoriasis
Chronic cutaneous discoid lupus
Tinea Corporis
Paget’s Disease
Lichen Planus
Bowen’s Disease
Cutaneous T-cell lymphoma (mycosis fungoides)
Pityriasis rosea
Secondary Syphilis
Ichthyosis
Describe Psoriasis
Oval, erythematous plaques
Extensor surfaces or sites of trauma
Pitting fingernails
Associated with asymmetric polyarthritis
What is the treatment of psoriasis if <5% of the body is involved?
Topical:
corticosteroids
Calcipotriene (Vit D3 analog)
Retinoids (tazarotene)
Systemic:
Calcineurin Inhibitors- Tacrolimus
Cyclosporine
What is the treatment of psoriasis if >5% of the body is involved?
Vitamin D analogs +/- phototherapy
Sysemtic/Biologic agents
What is the treatment for severe, recalcitrant disabling psoriasis?
Phototherapy, UVB
Systemic Agents:
Methotrexate
Acitretin
Cyclosporine
Apremilast
Anti-TNF agents
(Ex: Infliximab)
What is the differential for Bullous Lesions?
Herpes Simplex
Herpes Zoster
Impetigo
Dermatitis Herpetiformis
Burns
Bullous pemphigoid
Pemphigus Vulgaris
Eyrthema Multiforme
Porphyria Cutanea Tarda
Fixed drug eruption
Describe Herpes Zoster lesions
Vesicles of varying size on erythematous base
Typically in a single dermatome
Successive crops over 7 days followed by crusting for 2-3 weeks
How does Herpex zoster present?
Pre-eruptive pain, burning, itching (usually in one dermatome)
Fever, headache, malaise
Postherpetic neuralgia (pain after lesions clear up)
What is the treatment of Herpes Zoster?
Analgesics
Antiviral therapy- Acyclovir, Famciclovir, or Valacyclovir for 7 days
What is the role of corticosteroids in Herpes Zoster treatment?
May decrease pain in acute phase
No reduction in risk of postherpetic neuralgia
May increase risk of secondary infection
What is the treatment for postherpetic neuralgia?
Pregabalin or Gabapentin
TCAs
Opioids
Sympathetic nerve block - Bupivacaine
When is Shingrix (HZV) vaccine given?
50 years and older
Regardless of hx of varicella or other zoster vaccines
2 doses - 2 to 6 months apart
90% effective
Which vaccine is prefered for HZV?
Shingrix
Higher effectivity than Zostavax
What is the differential for pruritic erythematous papules?
Miliaria Rubra
Atopic dermatitis
Urticaria
Insect bites
Scabies
Pruritic papular Eruption
Pruritic urticarial papules and plaques of pregnancy (PUPPP)
What skin condition is commonly on flexor surfaces v. extensor surfaces?
Flexor- Atopic dermatitis
Extensor- Psoriasis
Describe scabies lesions
Curved or linear burrows
Vesicles or papules
Pustules indicated secondary infection
What is scabies?
Hypersensitivity reaction to Sarcoptes scabiei
May present with nocturnal pruritus
Where are scabies lesions commonly seen?
Axilla
Breasts
Elbows, wrists
Finger Webs
Waist
Buttocks, Genitals
How is scabies diagnosed?
Mark burrow with felt tip pen
Examine scraping under microscope with KOH or mineral oil
Mites will appear black
May also see eggs and feces