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USMLE Step 2 CK > Dermatology > Flashcards

Dermatology Flashcards

1
Q

squamous cell CA risk is greatly increased by long term use of

A

immunosuppressants (as in organ transplants)

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2
Q

recurrence rate of basal cell CA

A

<5%

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3
Q

Karposi Sarcoma is linked with which virus

A

HHV8

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4
Q

Kaposi Sarcoma affects which organs

A

skin, GI tract, lungs

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5
Q

Tx for kaposi sarcoma

A

antiretrovirals, vincristine or interferon injection, chemo (liposomal doxorubicin)

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6
Q

Tx for melanoma

A

surgery, interferon injection

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7
Q

what type of keratoses is premalignant

A

actinic

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8
Q

imiquimod is used for

A

actinic keratoses, mulloscum contagiosum, and condyloma acuminatum

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9
Q

Is atopic dermatitis exacerbated by food allergy

A

no

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10
Q

Tx for atopic dermatitis flares

A

topical corticosteroids

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11
Q

which Tx gets you off steroids for atopic dermatitis

A

T cell inhibitors (Tacrolimus and Pimecrolimus), but they are associated with lymphoma

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12
Q

Tx for atopic dermatitis with impetigo

A

antibiotics

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13
Q

Antihistamine Tx for severe atopic dermatitis

A

doxepine

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14
Q

Antihistamine Tx for mild atopic dermatitis

A

nonsedating (cetirizine, fexofenadine, loratidine)

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15
Q

steroids cause atrophy by inhibiting

A

collagen formation and growth

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16
Q

Tx of local psoriasis

A

topical high potency steroids, Vit A and D (calcipotriene), coal tar, pimecrolimus and tacrolimus

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17
Q

Tx of extensive psoriasis

A

UV light, antiTNF inhibitors, methotrexate

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18
Q

methotrexate effects which organs

A

liver/lung

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19
Q

antiTNF inhibitors side effect

A

reactivate TB, screen with PPD first

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20
Q

herald patch, spares palms and soles

A

pityriasis rosea

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21
Q

tx of pityriasis rosea

A

steroids or UV light

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22
Q

tx of seborrheic dermatitis

A

topical steroids and antifungals

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23
Q

pemphigus vulgaris is associated with which meds

A

ACEi, penicillamine, phenobarbital, penicillin

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24
Q

Bullae that rupture easy, nikolsky sign, mouth involvement

A

Pemphigus Vulgaris

25
Q

most accurate test for pemphigus vulgaris

26
Q

tx of pemphigus vulgaris

A

systemic steroids, azathoprine or mycophenolate gets off steroids, rituximab (anti CD20 antibodies) or IVIG

27
Q

bullae stay intact, milder disease

A

bullous pemphigoid

28
Q

most accurate test for bullous pemphigoid

A

biopsy with immunoflourescent stain

29
Q

best initial therapy for bullous pemphigoid

A

prednisone

30
Q

prophyria cutanea tarda is due to a deficiency in

A

uroporphyrin decarboxylase

31
Q

cause of porphyria cutanea tarda

A

liver (hep C), estrogen, excess iron

32
Q

porphyria cutanea tarda tx

A

treat underlying cause

33
Q

most accurate test for porphyria cutanea tarda

A

increased uroporphyrins in 24hr urine collection

34
Q

skin infections with Group A beta hemolytic strep causes

A

glomerulonephritis

35
Q

impetigo is caused by

A

staph and strep, superficial

36
Q

tx of mild impetigo

37
Q

tx of community acquired MRSA impetigo

A

clinda, TMP/SMZ

38
Q

erysipela is caused by

A

strep, deeper

39
Q

most accurate test for cellulitis

A

inject sterile saline into skin and aspirate for culture, 20% yield

40
Q

only cephalosporin covering MRSA

A

ceftaroline

41
Q

antistaph penicillins

A

ox, clox, diclox and Naf

42
Q

best initial test for fungal infections

43
Q

most accurate test for fungal infections

A

fungal culture

44
Q

best initial therapy for fungal infections

A

topical antifungal

45
Q

best therapy for hair/nail fungal involvement

A

terbinafine

46
Q

which antifungal is antiandrogenic

A

ketoconazole - causes gynecomastia

47
Q

tx for morbilliform rash

48
Q

drug hypersensitivity reaction, target lesions on trunk, no mucous membrane involvement

A

erythema multiforme

49
Q

tx of erythema multiforme

A

prednisone

50
Q

drug hypersensitivity reaction, mucous membrane involvement, negative nikolsky sign

A

stevens johnson syndrome

51
Q

drug hypersensitivity reaction, mucous membrane involvement, positive nikolsky sign

A

toxic epidermal necrolysis

52
Q

tx for steven johnson syndrome and TEN

53
Q

drugs associated with drug hypsensitivity rxns

A

penicillins, sulfa, allopurinol, phenytoin, lamotrigine, NSAIDs

54
Q

what looks like TEN with multiorgan involvement

55
Q

tx of SSSS and TSS

A

supportive, antistaph

56
Q

tx mild acne

A

benzoyl peroxide, topical antibiotics

57
Q

tx mod acne

A

topical vit A and oral antibiotics

58
Q

tx severe acne

A

oral vit A (isoretinoin) and oral antibiotics

USMLE Step 2 CK (11 decks)

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