Dermatology

Question 1

squamous cell CA risk is greatly increased by long term use of

Answer 1

immunosuppressants (as in organ transplants)

Question 2

recurrence rate of basal cell CA

Answer 2

<5%

Question 3

Karposi Sarcoma is linked with which virus

Answer 3

HHV8

Question 4

Kaposi Sarcoma affects which organs

Answer 4

skin, GI tract, lungs

Question 5

Tx for kaposi sarcoma

Answer 5

antiretrovirals, vincristine or interferon injection, chemo (liposomal doxorubicin)

Question 6

Tx for melanoma

Answer 6

surgery, interferon injection

Question 7

what type of keratoses is premalignant

Answer 7

actinic

Question 8

imiquimod is used for

Answer 8

actinic keratoses, mulloscum contagiosum, and condyloma acuminatum

Question 9

Is atopic dermatitis exacerbated by food allergy

Answer 9

no

Question 10

Tx for atopic dermatitis flares

Answer 10

topical corticosteroids

Question 11

which Tx gets you off steroids for atopic dermatitis

Answer 11

T cell inhibitors (Tacrolimus and Pimecrolimus), but they are associated with lymphoma

Question 12

Tx for atopic dermatitis with impetigo

Answer 12

antibiotics

Question 13

Antihistamine Tx for severe atopic dermatitis

Answer 13

doxepine

Question 14

Antihistamine Tx for mild atopic dermatitis

Answer 14

nonsedating (cetirizine, fexofenadine, loratidine)

Question 15

steroids cause atrophy by inhibiting

Answer 15

collagen formation and growth

Question 16

Tx of local psoriasis

Answer 16

topical high potency steroids, Vit A and D (calcipotriene), coal tar, pimecrolimus and tacrolimus

Question 17

Tx of extensive psoriasis

Answer 17

UV light, antiTNF inhibitors, methotrexate

Question 18

methotrexate effects which organs

Answer 18

liver/lung

Question 19

antiTNF inhibitors side effect

Answer 19

reactivate TB, screen with PPD first

Question 20

herald patch, spares palms and soles

Answer 20

pityriasis rosea

Question 21

tx of pityriasis rosea

Answer 21

steroids or UV light

Question 22

tx of seborrheic dermatitis

Answer 22

topical steroids and antifungals

Question 23

pemphigus vulgaris is associated with which meds

Answer 23

ACEi, penicillamine, phenobarbital, penicillin

Question 24

Bullae that rupture easy, nikolsky sign, mouth involvement

Answer 24

Pemphigus Vulgaris

Question 25

most accurate test for pemphigus vulgaris

Answer 25

biopsy

Question 26

tx of pemphigus vulgaris

Answer 26

systemic steroids, azathoprine or mycophenolate gets off steroids, rituximab (anti CD20 antibodies) or IVIG

Question 27

bullae stay intact, milder disease

Answer 27

bullous pemphigoid

Question 28

most accurate test for bullous pemphigoid

Answer 28

biopsy with immunoflourescent stain

Question 29

best initial therapy for bullous pemphigoid

Answer 29

prednisone

Question 30

prophyria cutanea tarda is due to a deficiency in

Answer 30

uroporphyrin decarboxylase

Question 31

cause of porphyria cutanea tarda

Answer 31

liver (hep C), estrogen, excess iron

Question 32

porphyria cutanea tarda tx

Answer 32

treat underlying cause

Question 33

most accurate test for porphyria cutanea tarda

Answer 33

increased uroporphyrins in 24hr urine collection

Question 34

skin infections with Group A beta hemolytic strep causes

Answer 34

glomerulonephritis

Question 35

impetigo is caused by

Answer 35

staph and strep, superficial

Question 36

tx of mild impetigo

Answer 36

mupirocin

Question 37

tx of community acquired MRSA impetigo

Answer 37

clinda, TMP/SMZ

Question 38

erysipela is caused by

Answer 38

strep, deeper

Question 39

most accurate test for cellulitis

Answer 39

inject sterile saline into skin and aspirate for culture, 20% yield

Question 40

only cephalosporin covering MRSA

Answer 40

ceftaroline

Question 41

antistaph penicillins

Answer 41

ox, clox, diclox and Naf

Question 42

best initial test for fungal infections

Answer 42

KOH

Question 43

most accurate test for fungal infections

Answer 43

fungal culture

Question 44

best initial therapy for fungal infections

Answer 44

topical antifungal

Question 45

best therapy for hair/nail fungal involvement

Answer 45

terbinafine

Question 46

which antifungal is antiandrogenic

Answer 46

ketoconazole - causes gynecomastia

Question 47

tx for morbilliform rash

Answer 47

none

Question 48

drug hypersensitivity reaction, target lesions on trunk, no mucous membrane involvement

Answer 48

erythema multiforme

Question 49

tx of erythema multiforme

Answer 49

prednisone

Question 50

drug hypersensitivity reaction, mucous membrane involvement, negative nikolsky sign

Answer 50

stevens johnson syndrome

Question 51

drug hypersensitivity reaction, mucous membrane involvement, positive nikolsky sign

Answer 51

toxic epidermal necrolysis

Question 52

tx for steven johnson syndrome and TEN

Answer 52

IVIG

Question 53

drugs associated with drug hypsensitivity rxns

Answer 53

penicillins, sulfa, allopurinol, phenytoin, lamotrigine, NSAIDs

Question 54

what looks like TEN with multiorgan involvement

Answer 54

TSS

Question 55

tx of SSSS and TSS

Answer 55

supportive, antistaph

Question 56

tx mild acne

Answer 56

benzoyl peroxide, topical antibiotics

Question 57

tx mod acne

Answer 57

topical vit A and oral antibiotics

Question 58

tx severe acne

Answer 58

oral vit A (isoretinoin) and oral antibiotics