Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

MCQ Review > Dermatology > Flashcards

Dermatology Flashcards

1
Q

Layers of the epidermis

A

Corneum
Granulosum
Spinosum
Basalis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Type of hypersensitivity reaction in atopic dermatitis

A

Type I (asthma, allergic rhinitis)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Type of hypersensitivity reaction in contact dermatitis

A

Type IV

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Pruritus, erythema, oozing, vesciles and edema, on the face and flexor surfaces; hx of asthma

A

Atopic dermatitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Dermatitis associated with exposure to allergens

A

Contact dermatitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Chronic inflammation of sebaceous glands and hair follicles due to hormone-related excess keratinization of hair shaft and excess sebum production

A

Acne Vulgaris

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Most common etiologic agent of acne vulgaris

A

C. acnes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Treatment of acne vulgaris

A 
Topical Retinoid/Vit. A - reduces keratin production
Topical antibiotics (clindamycin, erythromycin, dapsone), benzoyl peroxide products
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Well-circumscribed salmon colored plaques with silvery scale

A

psoriasis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

common areas of psoriatic lesions

A

extensor surfaces and scalp, in areas of TRAUMA (environmental trigger)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Excessive keratinocyte proliferation of prob. autoimmune etiology

A

Psoriasis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Auspitz sign

A

Psoriasis (pinpoint bleed)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Monroe microabscesses

A

Psoriasis (collection of neutrophils)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Treatment of Psoriasis

A

Corticosteroids
Immune modulating therapy
UV light (with psoralen) - to damage proliferating keratinocytes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

5Ps: pruritic, polygonal, papular, planar, purple

A

Lichen planus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

common areas of lichen planus

A

wrist, elbows, ORAL MUCOSA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Wickham striae

A

Lichen planus (reticular white lines)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Inflammation of dermal-epidermal junction

A

Lichen planus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Sawtooth appearance of dermal-epidermal junction

A

Lichen planus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

skin lesion Associated with chronic Hep C

A

Lichen planus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Autoimmune destruction of desmosomes (stratum spinosum) due to IgG antibodies agains desmoglein, leading to separation bet. basal cells and other cells of epidermis

A

Pemphigus vulgaris

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Tombstone appearance

A

Pemphigus vulgaris (basal cells attached via hemidesmosomes)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Fishnet appearance on immunofluorescence

A

Pemphigus vulgaris - IF highlights IgG

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

IgG antibody against basement membrane and hemidesmosomes causes subepidermal blisters

A

Bullous pemphigoid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

Differentiate Bullous pemphigois from pemphigus vulgaris

A

Both are blistering dermatoses - layers of skin are separated however

1) in PV separation is above basement membrane, in BP it separates the BM from the dermis
2) in PV oral mucosa is involved, in BP oral mucosa spared
3) in PV blisters rupture easily, form dried crust, in BP bullae do not rupture easily

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

Autoimmune IgA deposition on tips of dermal papillae, causing blistering

A

Dermatitis herpetiformis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

Blistering dermatoses Associated with celiac disease; improves w gluten free diet

A

Dermatitis herpetiformis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

Hypersensitivity reaction with targetoid rash and bullae

A

erythema multiforme

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

Type of hypersensitivity reaction assoc. with erythema multiforme

A

Type IV

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
30
Q

Erythema Multiforme versus SJS versus TEN

A

erythema multiforme + oral mucosa involvement + fever = SJS
10% BSA SJS
TEN is severe form usually associated with ADR >30% BSA , + sloughing of skin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
31
Q

Benign squamous proliferation in elderly, “stuck on” appearance

A

seborrheic keratosis

32
Q

Contains pseudocysts - circular spaces w pink keratin

A

seborrheic keratosis

33
Q

Sudden onset of multiple seborrheic keratoses suggesting underlying GI carcinoma

A

Leser- Trelat sign

34
Q

Epidermal hyperplasia with darkening of skin, velvet-like

A

acanthosis nigricans

35
Q

common areas of acanthosis nigricans

A

groin, axilla

36
Q

epithelial lesion Associated with insulin resistance or gastric CA

A

acanthosis nigricans

37
Q

elevated nodule with central ulceration and telangectasis; + pearly edge

A

Basal cell CA

38
Q

Elevated nodule on upper lip and/or non exposed skin

A

Basal Cell CA

39
Q

Histology: peripheral palisading

A

Basal cell CA

40
Q

Autosomal recessive defect in enzymes for nucleotide excision and repair leading to buildup of pyrimidine dimers in response to sunlight

A

xeroderma pigmentosum

41
Q

Ulcerated nodular mass on face or lower lip

A

squamous cell carcinoma

42
Q

Precursor to squamous cell ca; hyperkeratotic scaly plaque on face, back or neck

A

actinic keratosis

43
Q

Well-differentiated Squamous cell CA; rapid development, spontaneous regression

A

keratoacanthoma

44
Q

Cup-shaped tumor filled with keratin debris

A

keratoacanthoma

45
Q

Autoimmune melanocyte destruction causing localized loss of skin pigmentation

46
Q

congenital lack of pigmentation

47
Q

Enzyme defect in albinism

A

tyrosinase -> impaired melanin production

48
Q

small tan brown macule that darkens with sunlight exposure due to increased number of melanosomes

49
Q

mask-like hyperpigmentation of cheeks associated with pregnancy and OCP

50
Q

benign melanocyte neoplasm, with hair growth

51
Q

Most common cause of death from skin cancer

52
Q

Features of Melanoma

A

A - symmetry
B - orders are irregular
C - olor is not uniform
D - iameter >6mm

53
Q

Greatest risk factor for metastasis of melanoma

A

depth of invasion

54
Q

melanoma subtype with lentiginous proliferation along ED junction; only radial growth

A

lentigo maligna melanoma

55
Q

melanoma subtype involving superficial dermis; with dominant early radial phase

A

superficial spreading - most common subtype

56
Q

melanoma subtype with early vertical phase; poor prognosis

57
Q

melanoma subtype involving palms and soles, often in dark-skinned individuals

A

acral lentiginous

58
Q

Etiologic agents of impetigo

A

s. aureus, s. pyogenes

59
Q

erythematous macules, papules on face, with erosions, honey-colored crusts

60
Q

skin infection involving dermis; red, tender, swollen; increased risk with recent surgery, trauma, insect bites

A

cellulitis

61
Q

Necrosis of subcutaneous tissue under dermis due to anaerobic bacteria

A

necrotizing fasciitis

62
Q

Anaerobic bacteria causes CO2 production under dermi creating “bubbles” (crepitus; subcutaneous emphysema)

A

necrotizing fasciitis

63
Q

Etiologic agent of SSSS

64
Q

Exfoliative A and B toxins causes lysis of the skin and separation of layers, particularly the stratum granulosum; leads to skin loss

65
Q

Differentiate SSSS and TEN

A

TEN separation occurs at dermal-epidermal junction

SSSS separation of granulosum

66
Q

Flesh-colored papiule with rough surface

67
Q

Etiologic agent of Verruca

68
Q

Firm, pink umbilicated papule in children, as well as sexually active and immunocompromised adults due to pox virus

A

Molluscum Contagiosum

69
Q

Viral inclusions in molluscum contagiosum

A

molluscum bodies

70
Q

Skin lesions on pressure points of insensitive areas assoc. with diabetes, syphilis, leprosy, and other neuropathies

A

neuropathic ulcer

71
Q

cutaneous tanning caused by local application of heat

A

erythema ab igne

72
Q

Clusters of vesicular eruptions following CN V distribution

A

herpes zoster

73
Q

Painful, shallow ulcerated acute lesion, self limiting

A

herpes simplex

74
Q

Cafe au lait spots, pedunculated and sessile skin lesions, peripheral nerve distribution

A

neurofibromatosis type I Von Recklinghausen

75
Q

Diffusely painful subcutaneous fat deposition in middle aged women, around abdomen and thighs

A

adiposis dolorosa/ Dercum disease

76
Q

Treatment of recurrent paronychia

A

wedge resection

77
Q

treatment of pilonidal sinus

A

excision (kardyakis procedure with advancement flap)

MCQ Review (12 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions