Dermatology #3 Flashcards
MC type of skin cancer
basal cell carcinoma
Explain a basal cell carcinoma
slow growing, local invasion, no METs
MC on head, neck, trunk, nose
What does a basal cell carcinoma LOOK like
Small, raised, pearly, raised borders and central ulceration with telangiectasias that is friable (bleeds)
What diagnostic should be done for basal cell carcinoma
Punch or shave biopsy
Treatment for basal cell carcinoma
Moh’s for facial involvement
Cryotherapy, Imiquimod, 5-FU
2nd MC type of skin cancer
Squamous Cell Carcinoma
Risk factors for SCC
Sun exposure (biggest)
Actinic Keratosis
HPV Infection
What is Bowen’s Disease?
SCC in situ (hasn’t invaded the dermis yet)
Symptoms of a SCC
Erythematous, elevated nodule with white scaly or crusted, bloody margins
Nonhealing ulcer or erosion on the head, lips, hands, neck
Because a shave biopsy is often inadequate, what is the diagnostic of choice for SCC?
Punch or excisional biopsy
Treatment for SCC
-Surgical excision
-Moh’s, Imiquimod, 5FU
-Chemo if METs
MCC of skin-related cancer death
Melanoma
Where does a melanoma usually MET to?
Liver, lungs, lymph nodes, brain
Biggest risk factor for melanoma
UV radiation
Large number of nevi, tanning, etc.
What is the MC type of melanoma and where does it occur in both genders?
Superficial spreading
-Trunk in men
-Legs in women
What is acral lentiginous?
Type of melanoma that occurs in dark-skinned people on the palms, soles, nail beds
Explain ABCDE and how it relates to melanoma?
Symptoms of melanoma and when you should be suspicious
Asymmetry
Borders (irregular)
Color (varied)
Diameter (>6 mm)
Elevation
Diagnostics for melanoma
-Full thickness excisional biopsy + lymph node biopsy
How much should you excise based on size of melanoma?
> 1-2mm thick: take 2 cm
2-4 mm thick: 2cm marginal tissue
A Kaposi Sarcoma is associated with _______ and is predominantly in which population?
HHV8 infection
HIV with CD4 < 100
Symptoms of Kaposi Sarcoma and Treatment
Painless, nonpruritic macular papule or nodules brown, red in color, plaque or violaceous lesions
HAART therapy if HIV related
Chemotherapy
Condyloma Acuminata are _______ and appear as cauliflower like lesions on the genitals. How do you diagnose these?
Genital warts
Whitening of the lesion with acetic acid
Although 80% of condyloma acuminata spontaneously resolve, what are some treatment options?
Cryotherapy
Topical Podofilox
What is the vaccine given to prevent genital warts and what is the schedule?
2 doses, 6 months apart
Gardasil 9: 6, 11, 16, 18, 31, 33, 45, 52, 58
Name the 9 HPV strains protected against in Gardasil 9. Is this vaccine safe in pregnancy?
6, 11, 16, 18, 31, 33, 45, 52, 45
Not safe in pregnancy
Molluscum Contagiosum is due to _______ and appears as
Poxvirus
Discrete, dome-shaped flesh colored or pearly waxy papules with central umbilication