Dermatology Flashcards
Pustule
Small raised lump containing pus. Creamy-coloured, will see neutrophils if you put it on a slide.
Papules
Small raised lumps <1cm
Nodules
Small raised lumps >1cm
Macule
Large lesion, usually less raised
Wheal
AKA hives. Pruritic, erythematous sites.
Urticaria
When wheals form all over the body in response to an allergic reaction.
Vesicles
Sharply circumscribed elevations filled with fluid. Commonly caused by viral infections.
Bullae
Larger vesicles
Erosion
Partial loss of the epithelium, the basement membrane is INTACT. No innervation in epidermis so the animal may not even notice. As the basal layer is intact the cells are able to regrow very quickly.
Ulceration
FULL THICKNESS- the basement membrane is BROKEN. Appear bloody, fluidy (cause of leakage of proteinaceous fluid). PAINFUL- may have loss of pigment and adnexal structures (alopecia) depending on severity.
Lichenification
The skin takes on a thickened, crumpled appearance. Can occur everywhere but usually more evident in hairless regions. Usually indicates SYSTEMIC disease.infection
Comedone
Effectively a pimple- swollen hair follicles.
Epidermal collarettes
Effectively “old” pustules- ring of peeling skin?
Depigmentation
Loss of pigment. Done purposefully in freeze branding
Tumour
= Mass/lump. May be neoplastic (benign or malignant), inflammatory etc
Crusting
Retention of the surface cells (i.e.the surface epithelium that is usually shed regularly) along with other debris, incl sebum, inflam cells etc.
Dehiscence
The breaking down of a wound i.e. sutured site opening up again, esp after surgery.
Erythema
= Redness, generally due to > blood flow
Alopecia
Hair loss- due to disruption of adnexal structures.
What is the function of fat in the hypodermis?
Cushioning, thermoregulation, storage of energy.
Panniculitis
Inflam involving the hypodermis
Cellulitis
Inflam involving underlying fascial planes as well as the panniculus and sometimes other parts of the skin.
Phelgmon
Spreading diffuse inflam process w/ formation of suppurative/purulent exudate or pus caused by infection.
What are the 3 causes of photosensitisation?
- Genetic disorders that lead to production of photoactive compounds- this is rare.
- As a result of ingestion of plants that contain primary photosensitising agents- they directly cause it.
- Ingestion of plants/other causes of cholestatic hepatic disease- this results in phylloerythrin in herbivores, resulting in 2’ photosensitisation.