Dermatology Flashcards
Blueberry muffin lesions are due to…
dermal erthyropoiesis
(observed in CMV and Rubella)
cafe au lait spots, how many concerning for NF Type 1?
5 or more
What is next step in management with 5 or more hemangioma
Abdominal ultrasound, echo
Name some syndromes with Port Wine Stain
Sturge Weber
Beckwidth Weideman
Cobb Syndrome
Klippel- Treunay
Waardenburg Syndrome (Name some features)
Autosomal dominant
hypopigmented patches of hair
congenital nerve deafness
craniofacial abnormalities
what causes umbilical granuloma?
due to umbilicus not re-epethializing
What is most common skin infection in children?
non-bullous impetigo
What is aplasia cutis congentia
congenital absence of skin involving epidermis and dermis.
What does fluid culture show in Staph Scalded skin sydnrome?
Nothing as it is sterile
Sebaceous Nevus
CHARGE disorder
Coloboma
Heart Defect
Atresia of choana
Renal anomalies
Genital Hypoplasia
Ear anomalies
What are milia?
pearly, non-erythematous, yellow or white papules evident over face
small epidermal inclusion cysts.
What condition has Wright Stain that shows numerous neutrophils?
Neonatal pustular melanosis
What condition has Wright Stain that shows numerous eosinophils?
Erythema Toxicum
Where is cell free DNA derived from?
placena, continuous turnover of villous trophoblast, results in shedding of apoptotic material including cell free DNA
harlequin ichthyosis causes what possible eye findings?
inversion of eyelids, keratitis, corneal abrasion
due to drying of eyes
hyperkeratotic plates cause tension on the eyelids, leading to bilateral inversion of the conjunctiva
Diagnosis of Bullous Pemphigoid
linear pattern of IgG and C3 along basement membrane zone on immunofluroescent staining
tense blisters on hands and feet
Diagnosis of Bullous Impetigo
Clinical
vesicles that enlarge into non-tender flaccid subcorneal bullae with thin erythematous base
but can be confirmed by gram stam and culture of bullae’s fluid
What are the 4 types of Ezpidermolysis bullosa?
4 types are defined based on where blistering occurs
Simplex (basal epidermal above BMZ)
Junctional (through BMZ)
dystrophic (superficial dermis)
mixed
2 ways in which Epidermolysis Bullosa presents after birth
skin fragility with erosions and bullae often occurring secondary to minor friction
Dramatic presentation localized absence of skin, well demarcated extensive erosions on lower limbs
What is the layer of skin that conserves body bater and serves as barrier protection?
startum corneum
When will symptoms of acrodermatitis enteropathica (zinc deficiency) first appear?
around 1 year of life when infant transitions to cow’s milk, or to formula after breastfeeding.
impaired zinc absorption.
Autosomal Recessive
What other lab abnormalities do you see in SCFN
thrombocytopenia, hypertriglyceridemia, and hypercalcemia.
