Dermatology Flashcards
Most common cancer associated with acanthosis nigricans
Gastric adenocarcinoma
Other associations;
* T2DM
* PCOS
* Acromegaly
* Cushing’s
* Hypothyroidism
* COCP
* Nicotinic acid
Management of impetigo
Hydrogen peroxidase or Topical fusidic acid
Bowen’s disease
Pre-cancerous dermatoss (5% come SCC)
Features;
* 10-15mm sized flat erythematous scaly patch on sun exposed areas e.g Head
Treatment = topical 5-Flurouracil
Schoole exclusion rules for child with impetigo
Can return to school 48hrs after commencing treatment
Treatment for facial hirtuism
Topical eflorithine
- blocks putrescine therefore preventing hair growth
Nikolksy’s sign
When the epidermis separates away from the dermis with mild pressure applied
Happens in steven-johnsons syndrome
Mx = move to intensive care
Which medication is known to exacerbate plaque psoriasis
Beta-blockers
Also: NSAIDs, lithium, ACEi, antimalarials + withdraw of steroids
What is the most common malignancy secondary to immunosupression
Skin cancer - Squamous cell carcinoma (SCC)
What effect does hydroxychloroquine have on the eye
bulls eye maculopathy
Melanoma vs seborrhoeic keratosis
Melanoma usually has more variation in shape and colour whereas seborrhoeic keratosis often has a ‘stuck-on’ greasy brown appearance.
Venus ulceration is most commonl seen above the
medial malleolus
Erythema nodosum
Tender, raised, erythematous lesions - typically on shins, forearms and thighs
Typically better in 6 weeks without scarring
Causes;
* Sarcoidosis
* SLE
* Infection - may present following flu-like Sx.
* TB
* IBD
* Behcets
* Malignancy
* Pregnancy
* Drugs e.g penecillins
Erythema ab igne
Typically caused by radiation or hot water bottles
Erythema multiforme
Begins as red patches over hands and then develops into target lesions
Thought to be immune mediated - often caused by viral, fungal or bacterial infections
