Dermatology

Question 1

Associations with alopecia accreta

Answer 1

Nail changes, Downs Syndrome, autoimmune thyroid disease

Question 2

Flaccid blisters, intra-epidermal splitting, acantholysis

Answer 2

Pemphigus vulgaris

Question 3

Tense blisters, sub-epidermal splitting

Answer 3

Bullous Pemphigoid

Question 4

Autoantibodies against desmosomes

Answer 4

Phemigus vulgaris

Question 5

Antibodies against hemi-desmosomes

Answer 5

Bullous pemphigoid

Question 6

Scaly dry skin on fingers

Answer 6

Ichthyosis (disorder of cornification)

Question 7

Rash appears as a result of hypersensitivity to HSV

Answer 7

Erythema multiforme

Question 8

Management of vitiligo

Answer 8

Suncream

Question 9

Characteristic light brown macular rash

Answer 9

Cafe au lait spots (associated with NF1)

Question 10

Features of NF1

Answer 10

2 or more of the following:
-6 or more cafe au lait patches larger than 5mm in children or larger than 15mm in adults
-2 or more neurofibromas
-Axillary or groin freckling
-Optic pathway glioma
-2 or more Lisch nodules (pigmented iris hamartomas)
-Bony dysplasia
-First degree relative with NF1
-

Question 11

Vesicular dermatitis on hands and feet

Answer 11

Pompholyx

Question 12

Red man syndrome, associated hypoproteinaemia, high output heart failure, hypothermia

Answer 12

Erythrodermic psoriasis

Question 13

Scaly, crazy paving pattern on shins, often in eldery

Answer 13

Asteatotic Eczema

Question 14

Nails: yellow, slow growing, onycholysis present. Associated with lymphodema

Answer 14

Yellow nail syndrome

Question 15

Nails stained blue/green

Answer 15

Associated with tetracyclines

Question 16

Drugs which can precipitate psoriasis

Answer 16

Lithium, beta blockers

Question 17

Skin conditions which deteriorate through pregnancy

Answer 17

SLE, Herpes simplex, acne rosacea

Question 18

Sign of severe venous insufficiency

Answer 18

Atrophie blanche (star shaped white atrophic scar surrounded by areas of hyperpigmentation)

Question 19

Ulcer at site of scar, non-healing

Answer 19

Marjolin’s ulcer

Question 20

Scaly skin, intense itch, worse with repeated washing

Answer 20

Xerosis

Question 21

Which disease are you at significant increased risk of developing if you have psoriasis?

Answer 21

Cardiovascular, non-alcoholic fatty liver disease, T2DM, HTN

Question 22

Conditions associated with erythema nodosum?

Answer 22

TB, IBD, Sarcoidosis

Question 23

Granuloma annulare

Answer 23

Associated with diabetes, persists for many years, lacks effective treatment

Question 24

26 year old with psoriasis has used strong steroid and vitamin D analogue once a day for 8 weeks with no improvement. What next?

Answer 24

Stop steroid and continue Vit D analogue twice daily

Question 25

Severe cutaneous hypersensitivity reaction, Nicolsky’s sign and affecting 45% of the body

Answer 25

Toxic epidermal necrolysis