Dermatology Flashcards
Associations with alopecia accreta
Nail changes, Downs Syndrome, autoimmune thyroid disease
Flaccid blisters, intra-epidermal splitting, acantholysis
Pemphigus vulgaris
Tense blisters, sub-epidermal splitting
Bullous Pemphigoid
Autoantibodies against desmosomes
Phemigus vulgaris
Antibodies against hemi-desmosomes
Bullous pemphigoid
Scaly dry skin on fingers
Ichthyosis (disorder of cornification)
Rash appears as a result of hypersensitivity to HSV
Erythema multiforme
Management of vitiligo
Suncream
Characteristic light brown macular rash
Cafe au lait spots (associated with NF1)
Features of NF1
2 or more of the following:
-6 or more cafe au lait patches larger than 5mm in children or larger than 15mm in adults
-2 or more neurofibromas
-Axillary or groin freckling
-Optic pathway glioma
-2 or more Lisch nodules (pigmented iris hamartomas)
-Bony dysplasia
-First degree relative with NF1
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Vesicular dermatitis on hands and feet
Pompholyx
Red man syndrome, associated hypoproteinaemia, high output heart failure, hypothermia
Erythrodermic psoriasis
Scaly, crazy paving pattern on shins, often in eldery
Asteatotic Eczema
Nails: yellow, slow growing, onycholysis present. Associated with lymphodema
Yellow nail syndrome
Nails stained blue/green
Associated with tetracyclines
Drugs which can precipitate psoriasis
Lithium, beta blockers
Skin conditions which deteriorate through pregnancy
SLE, Herpes simplex, acne rosacea
Sign of severe venous insufficiency
Atrophie blanche (star shaped white atrophic scar surrounded by areas of hyperpigmentation)
Ulcer at site of scar, non-healing
Marjolin’s ulcer
Scaly skin, intense itch, worse with repeated washing
Xerosis
Which disease are you at significant increased risk of developing if you have psoriasis?
Cardiovascular, non-alcoholic fatty liver disease, T2DM, HTN
Conditions associated with erythema nodosum?
TB, IBD, Sarcoidosis
Granuloma annulare
Associated with diabetes, persists for many years, lacks effective treatment
26 year old with psoriasis has used strong steroid and vitamin D analogue once a day for 8 weeks with no improvement. What next?
Stop steroid and continue Vit D analogue twice daily
Severe cutaneous hypersensitivity reaction, Nicolsky’s sign and affecting 45% of the body
Toxic epidermal necrolysis
