Dermatology Flashcards
2Topical Rx for psoriasis (1st line)
Corticosteroids
Calcipotriol
Topical Rx for psoriasis (2nd line)
Dithranol
Salicylic acid 3%
Coal tar 2%
Tazarotene
Systemic Rx for psoriasis
1- MTX 7.5-30 mg weekly as 3 doses 12hr interval . (hepatotoxic)
2- cyclosporin (nephrotoxic)
3- acitretin -in pustular & erythrodermic PS (teratogenic)
Biologic drugs for psoriasis
1- alefacept (pathogenic T-cell)
2- Efalizumab (T-cell activation)
3- Etanercept & infliximab (anti TNF)
warts treatment
1- cautary
2- liquid nitrogen
3- Blunt dissection (for large)
4- aspirin (topical)
5- Imiquimod creeeeeeeeaaaaaam
topical Rx for pruritus
soothing lotion i.e calamine
steroid cream
coconut
1% menthol in 90% ethanol
topical antipruritic drugs i.e doxepin
eczema Rx
1- education
2- topical : CS & calcinuriens inhibitor (tacrolimus &pimecrolimus
3- anti-inflamm. (steroid) || immunosuppressives
Urticaria Rx
Soothing lotion (calamine)
Anti histamine H1 and h2
Corticosteroid.
In chronic
anti H (Doxepin 25-50 mg OD )
Corticosteroid
Cyclosporine (2.5 _ 5 mg)/kg/d
Immunoglobulin (I.V)
• Other drug treatments are ketotifen (1-2 mg daily at night), disodium cromoglycate, beta agonist (terbutaline 2.5 mg three times daily), calcium channel blockers (nifedipine), leukotriene antagonists (montelukast
Leishmania Rx
stiboglu
Impetigo contagiosa
- crust removing > topical fusidic acid
- oral flucloxacillin || (cephalexin || cefadroxil) for 5-10 Days. (treatment for ecthyma also)
cellulitis & erysipelas
flucloxacillin (500mg) every 6 Hr or cephlosporin
Furuncles and carbuncles
Treatment: Many furuncles are self-limited and respond well to frequent applications of a moist warm compress. The primary management of cutaneous abscesses should be incision and drainage. The abscess is not ready for drainage until the skin has thinned and the underlying mass becomes soft and fluctuant. Anti-staphylococcal antibiotics for 5-10 days
sycosis barbae Rx
fusidic acid
cephalexin for 2 Wks in extensive cases
vitiligo Rx
1- potent topical cortecosteroid
2- calcinurin inhibitors i.e tacrolimus ointment
3- psoralin (trimethylpsoralen || methoxypsoralen) taken before 2 hrs of uva exposure
4- UVB 2-3 weekly for 6 mo.
5- skin graft
6- excimer laser
7- minigraft
8- melanocyte || stem cell transplant
chloasma Rx
-sunscreen
-bleaching agents contain hydroquinone for 6-10 Wks
in stubborn > add steroid and retinoid
-chemical peels such as glycolic acid
Impetigo contagiosa
Fucidic acid & oral cephalexin
Ecthyma
Cephalexin
Sycosis barbae
Stop shaving
Cephalexin
Oral corticosteroid
Erysipelas / cellulitis
Erysipeloid
Oral cephalexin
Erythrasma
Oral or topical erythromycin
Verruca plana ,
Filiform wart
Tretinoin
Curettage respectively
Varicella
Antipyretic
Antipruritic (Hydroxyzine)
Cephalexin
Acyclovir
Molluscum contagiosum
Curettage
Tinea pedis
Terbinafine cream 1% ( 2 D for 1 W)
{Fluconazole 50mg 1 W for 4 W || Itraconazole 200mg 2 D for 1 W || Terbinafine 250mg 1 D for 2 W} for moccasin and vesicular tinea
Topical steroid can be used if there is reaction
Tinea cruris
Terbinafine 1% (twice daily for one week)
Fluconazole 150mg once weekly for 2-4
Itraconazole 100mg twice daily for 1 week
Terbinafine 250mg once daily for 1-2 week
Pityriasis versicolor
Treatment options:
Ketoconazole shampoo 2% (Nizoral) daily application for 3 days.
Selenium sulfide suspension 2.5% (Selsun) applied for 10 minutes every day for 7
consecutive days.
Itraconazole 200mg once daily for 1 week. Prophylaxis: 200 mg twice 1 day per month for
6 months for recurrent disease.
Fluconazole 300mg single oral dose. Repeated in 2 weeks if needed.
Ketoconazole 400mg single oral dose. Prophylaxis: 400mg once monthly for recurrent
disease.
Tinea capitis
Griseofulvin 20 mg/kg/day ||
Fluconazole (Diflucan) 8 mg/kg once weekly for 4-16 weeks.
Terbinafine (Lamisil) 20-40 kg body weight: 125 mg daily 2-4 weeks, >40 kg body weight:
250 mg daily 2-4 weeks
Herpes zoster
Acyclovir 800mg 5 times a day for 5 days
Lichen planus
Topical and systemic steroid
Phototherapy
Antihistamine
Cyclosporin
Scabies Rx
Education
Topical sulphur for 3 days and then topical permethrin at night , another permethrin after 5 days
Local vitiligo
1-Sun Screen.
2- Local Steroid.
3- Tacrolimus.
4- Cosmetic Comuflag Cream.
Diffuse vitiligo
1- PUVA.
2- Systemic Steroid.
3- U.V.B Rays.
4- If More than 90% of Skin Affected; DoÆ De-Pigmentation by; Ethyl Ether Hydroquinone
Acne
(According to the Grade)
-Local Treatment: Local Retinoid, Benzyl Peroxide, Local AB. -Systemic Treatment: Systemic Retinoid, Systemic AB.
Rosacea
1- Avoid Sun Light. 2- Systemic Retinoids. 3- Systemic AB. 4- Mitronidazole Cream.
Acute paronychia
Incision»_space;> cephalexin
Chronic paronychia
Dry
Topical clotrimazole
Mixture of anticandida , antibiotics, steroid (nystatin , neomycin , gramicidin , triamcinolone)
Fluconazole 150 for 4 W
Onychomycosis
1- Terbinafine 250mg daily for 6 W in finger nail while 12 W for toenail
Itraconazole (Sporanox 100mg capsule) is a fungistatic agent. Pulse dosing: A pulse
treatment consists of two capsules (200 mg) twice daily for one week, followed by a 3-week
drug free interval. Two to 3 pulse treatments are recommended for fingernail infections and
