Angina

Question 1

Nifedipine

Answer 1

It is ca channel blocker

Cannot be used in angina due to reflex tachycardia

Question 2

Ivaradine

Answer 2

Block na channel in sa node , so it will decrease the current of the heart , it used instead of beta-blocker if can’t used …
Outcome is bradycardia

Question 3

Ranolazine

Answer 3

It is PFOX but its main mechanism is to block Na channel so Ca will decrease ==> weak contraction

Question 4

Bisoprolol , metoprolol , carvedilol

Answer 4

Best B-blocker used for angina

Question 5

Isosorbide

Answer 5

It is oral form (like nitroglycerine)

Question 6

Nicorandil

Answer 6

Potassium channel blocker => relaxation + vasodilation

Question 7

Families of ca++ channel blocker

Answer 7

1) phenylalkylamines ====> verapamil
.
2) dihydropyridine      ====> nifedipine , Amlodipine
.
3) Benzothiazepine    ====> Diltiazem

Question 8

Nemodipine

Answer 8

It is Ca++ channel blocker .

it has a selectivity to cerebral vessels , so it is beneficial after subarachnoid hemorrhage to reduce vasospasm .

Question 9

Notes

Answer 9

Amlodipine has longer half-life than other.

All ca blockers cause heart block , ankle edema , constipation