Dermatology

Question 1

Describe incontinentia pigmenti

Answer 1

X Linked dominant
IKBKG gene
Lethal in males

Linear inflammatory vesicles—>
Pigmented warts —>
Whorls on trunk + extremities —>
Hypogmemted atrophic

** Evaluate for assoc’d defects (80% CNS, eye, dentition)

Question 2

Hemangioma

Answer 2

Greater in female and preterm

If liver or large cutaneous - high output CHF ♥️
If parotid or liver - assoc’d with teansient hypothyroidism

Question 3

Describe Aplasia Cutis Congenita

Answer 3

AD (benign form)
Hair collar sign - assic’d with NTD
Scalp erosion or ulceration (» occiput)

Majority scalp not with genetic abnormality

Assoc’d with limb defects, cleft lip/pakate, epidermal nevi and T13 or 4p del

Complication includes hémorrage (eschar pulling from dura)

Question 4

Well defined red plaques
Adherent silver white scale
Extensor arms and legs
Scalp

Answer 4

Neonatal psoriasis

Rare

Question 5

Isolated vesicles rupture
Hiney colored crusts
Erythrma rim
Genital area and abdomen

Answer 5

Bullous impetigo

Staphylococcus aureus localized toxin effects

Question 6

Congenital dermal melanocytosis is assocd with ____

Answer 6

Gangliosidosua type 1

Hunter syndrome

Question 7

Where is nevus of ota located?

Where is the distribution

Answer 7

Unilsteral on face

Distribution of trigeminal neeve

Increased risk of melanoma
R/O glaucoma
This congenital dermal melanocyte does NOT fade

Nevus of Ito is located along shoulder/ scapula area

Question 8

What is LEOPARD

Answer 8

Lentigines 
EKG Conductuon defect 
Ocular hypertension 
Pulmonary stenosis
Abnormal genitalia 
Restriction of growth 
Deafness

Rash (small brown macules) noted at birth

Question 9

AD
Mutation in keratin 1 or 19
Scaling of skin
Epidermal hyper proliferation and fragility

Answer 9

Epidermolytic ichthyosis

Question 10

Where does psoriasis present in the newborn period?

Answer 10

Diaper (no silver plaque)
Scalp

Well defined red plaques with adherent silver - white scale
Usu extensor arms, legs, diaper area, umbilical area, scalp

Question 11

Term NBN DOL 3
Nontender blisters on abdonen with thin rim erythema filled with cloudy yellow fluid
Easily rupture —-> glossy erosions with scale crust left

What will you see on gram stain?

Answer 11

Staph

Bullous impetigo -
Due to staph aureus exotoxin

Tx - antibiotics

Question 12

2 wk old
Fever, poor feeding, irritable
Face has turned ‘bright red’ and started ‘to blister’
Flaccid bullae on face and trunk which easily rupture
Conjunctivae injected
Crusting around eyes and mouth

What is dx?
What is tx?

Answer 12

Staph Scalded Skin

Abx

Gram stain negative- sterile fluid

Question 13

What is EB associated with

Answer 13

Cutis Aplasia

Pyloric stenosis

Question 14

Incontinentia pigmenti shows which tzanck smear

Answer 14

Eosinophils