Dermatitis Flashcards
What is contact allergic dermatitis
A type 4 hypersensitivity reaction caused by contact exposure to an allergen
Presentation of contact allergic dermatitis
Onset 24-72hrs in a previously sensitised individual
Sparing of non-exposed areas - often sharp cut off where allergen ends
Itch
Burning
Erythema
Vesicles & bullae
Ix for suspected contact allergic dermatitis
Diagnostic - Patch testing
Consider skin biopsy
Histological appearance of contact allergic dermatitis
Spongiotic dermatitis
Tx of contact allergic dermatitis
- Topical Corticosteroids - appropriate for severity
2. Calcineurin inhibitors
Mild TCS
Hydrocortisone 0.1%
Moderate TCS
Modrasone Clobetasone Butyrate
Potent TCS
Betamethasone Valerate
Very potent TCS
Clobetasol
Examples of calcineurin inhibitors
Tacrolimus topical
Pimecrolimus topical
What is contact irritant dermatitis
A non-specific physical irritation rather than a specific allergic reaction
Presentation of contact irritant dermatitis
Occurs within mins-hours of a severe irritant
Itch
Burning
Erythema
Vesicles & bullae
Tx of contact irritant dermatitis
Same for contact allergic - topical corticosteroid appropriate for severity
Side effects of topical corticosteroids
skin thinning
purpura
stretch marks
What is eczema herpeticum
Severe primary infection of the skin by herpes simplex virus 1 or 2