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Step2CK > Derm Uworld > Flashcards

Derm Uworld Flashcards

1
Q

common spots for warfarin induced necrosis

A

breast, buttocks,thigh and abdomen

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2
Q

managment of warfarin induced necrosis

A

Vit K and warfarin discontinued if necrosis continues

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3
Q

leading cause of sepsis psot burn

A

infection of staph or pseudomonas

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4
Q

child with complicated hemangioma, management?

A

beta blockers

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5
Q

type of hemangioma on infant

A

superficial

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6
Q

type IV HS

A

delayed

T cell and macrophage mediated

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7
Q

Which HS is autoAb mediated

A

Type II

IgG and IgM

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8
Q

which HS is Ab-Ag immune complex

A

type III

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9
Q

2 day old has scattered erythematous macules and papules all over body

A

erythema toxicum neonatorum

no Tx

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10
Q

Tx staph scalded skin syndrome

A

oxacillin, nafcillin or vanco

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11
Q

dermatitis herpetiformis

A

erythematous papules and vesicles and bullae that are symmetric in herpetiform arrangement on extensor surfaces, upperback and buttocks

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12
Q

dermatitis herpetiformis is assoc with

A

gluten sensitive enteropathy (celiacs)

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13
Q

Tx for dermatitis herpetiformis

A

dapsone

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14
Q

eczema herpeticum

A

primary HSV infection
painful vesicles with punched out erosions and hemorrhagic crusting
fever and lymphadenopathy are common

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15
Q

Tx for eczema herpecticum

A

acyclovir

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16
Q

18 year old Tx for acne has extreme reaction to sunburn

A

doxycycline induced phototoxicity

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17
Q

ichthyosis vulgaris

A

normal skin at birth with progression to dry scaly skin
horney plates over extensor surfaces
sparing of face and diaper area
worsens in winter

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18
Q

senile purpura is from what

A

perivascular CT atrophy

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19
Q

farmer with persistent ulcer on lower lip

A

squamous cell carcinoma is most common

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20
Q

what would you find on Bx of SCC

A

invasive cords of squamous cells with keratin pearls

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21
Q

histo shows invasive clusters of spindle cells surrounded by palisaded basal cells

A

BCC

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22
Q

scaly erythematous patch on scalp that progresses to alopecia with residual black dot

A

tinea capitis

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23
Q

pityriasis versicolor

A

malassezia globosa
hypopigmented lesions
fine scale
pruritis

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24
Q

Dx pityriasis versicolor

A

KOH preparation show hyphae and yeast cells in spaghetti and meatbals pattern

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25
Q

Tx of pityriasis versicolor

A

topical ketoconazole, terbinafine or selenium sulfide

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26
Q

which skin cancer has perineural invasion causes numbness and paresthesias

27
Q

marjolin ulcer

A

SCC in a burn wound

enlarging nodule with persistent drainage

28
Q

Tx bullous pemphigoid

A

topical clobetasol

29
Q

what causes bullous pemphigoid

A

IgG autoAb against hemidesmosome and BM zone

30
Q

skin Bx of bullous pemphigoid

A

IgG and C3 deposits along BM

31
Q

clobetasol

A

high potency topical corticosteroid

32
Q

what drug can trigger shingles

A

tnf alpha inhibitors

33
Q

what type of HS rash is scabies

34
Q

what drugs likely cause stevens johnson syndrome

A

sulfonamides, NSAIDs anticonvulsants and allopurinol

35
Q

difference steven johnson syndrome and toxic epidermal necrolysis

A

SJS 30% body surface

36
Q

snad paper like skin lesion

A

actinic keratosis

37
Q

dermatofibroma

A

benign fibroblast proliferation
firm hyperpigmented nodules on lower extremities
dimpling in center when pinched!

38
Q

skin tags are assoc with

A

insulin R
pregnancy
crohns

39
Q

porphyria cutanea tarda is assoc with

40
Q

sudden onset severe psoriasis assoc with

41
Q

severe seborrheic dermatitis assoc with

A

HIV

parkinson

42
Q

pyoderma gangrenosum assoc with

43
Q

explosive onset multiple itchy seborrheic keratosis

A

GI malignancy

44
Q

what to use for topical glucocorticoid replacement for face

A

tacrolimus

45
Q

Tx tinea corporis

A

clotrimazole or terbinafine topicals

46
Q

monomorphous erythematous papules in someone with SLE

no comedomes

A

medication side effect
steroid induced folliculitis
prednisome

47
Q

what autoimmune diseases are assoc with vitiligo

A 
pernicious anemia, autoimmune thyroid like graves
type I DM
primary adrenal insufficiency
hypopituitarism
alopecia areata
48
Q

staph scalded skin syndrome

worse in kids or adults

49
Q

what to do for frsotbite

A

rapid rewarming with warm water

50
Q

pemphigus vulgaris

A

easy separation of epidermis on superfiical pressure
IgG deposits intercellularly in epidermis
AutoAb againse desmoglein

51
Q

Tx pemphigus vulgaris

52
Q

bullous pemphigoid

A

no oral lesions
benign
tense blisters
IgG and C3 deposits

53
Q

tx for moderate inflammatory acne

A

topical retinoids
benzoyl peroxide
add topical antibiotics

54
Q

Tx porphyria cutanea tarda

A

phelbotomy
hydroxychloroquine
INF alpha with Hep C patients

55
Q

HSP

A

IgA mediated luekocytoclastic vasculitis

56
Q

sings of HSP

A 
palpable purpura
arthritis
abdominal pain
intussusceptions
renal disease like IgA nephropathy
57
Q

Tx HSP

A

supportive hydration and NSAIDs

cna hospitalize with sytemic glucocorticoids if severe

58
Q

renal Bx in HSP

A

IgA deposition in mesangium

59
Q

erysipelas

A

strep
limited to epidermis and dermis
raised sharp borders with intense erythema

60
Q

Graft versus host is acittvaiton of what

A

donor T lymphocytes

61
Q

organs effected in graft vs host

A

skin intestine and liver

62
Q

where does vitiligo preferentially occur

A

around orifices

63
Q

what causes vitiligo

A

autoimmune destruction melanocytes

Step2CK (26 decks)

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