Derm Pharm

Question 1

Broad spectrum antimicrobial that can be safely used on skin and oral mucosa

Answer 1

Chlorhexidine

Question 2

Petrolatum, lanolin, dimethicone, mineral oil

Answer 2

Emollients (trap water in skin)

Question 3

Glycerin, lecithin, propylene glycol

Answer 3

Humectants (draw water to skin surface)

Question 4

alpha hydroxyacids, salicylic acid, urea, allantoin

Answer 4

Horny substance softeners (break down keratin)

Question 5

PABA, benzophenones, dibenzoylmehtanes, titanium dioxide

Answer 5

Sunscreen components

Question 6

bacitracin, neomycin, polymixin B

Answer 6

Topical antibacterial agents (Neosporin)

Question 7

Brimonidine, -zolines

Answer 7

topical vasoconstrictors

Question 8

Salicylic acid and imiquimod

Answer 8

wart removers

Question 9

calamine, menthol, camphor, capsacian, hydrocortizone, doxepin, pramoxine

Answer 9

anti-itch

Question 10

PDGF drug that is approved for chronic diabetic foot ulcers

Answer 10

Becaplermin

Question 11

Topical antifungals used for vulvovaginal candidiasis

Answer 11

miconazole and clotrimazole

Question 12

Topical antifungal for onychomycosis

Answer 12

efinaconazole

Question 13

Topical antifungal that can be in a shampoo for seb derm

Answer 13

ketoconazole

Question 14

Rx broad spectrum antifungal that disrupts macromolecular synthesis; tx for dermatophytes candida and malassezia

Answer 14

Ciclopirox

Question 15

Antifungal that inhibits squlane epoxidase and is highly effective against dermatophytes

Answer 15

Terbinifine

Question 16

Antifungal that alters membrane permeability and used to treat oral and cutaneous Candida

Answer 16

Nystatin

Question 17

Antifungal that alters membrane permeability and used to treat cutaneous Candida and IV for disseminated fungal infection

Answer 17

Amphotercin B

Question 18

Tx for orolabial HSV infection

Answer 18

Acyclovir

Question 19

Pruritis tx; TRPM8 agonist

Answer 19

Menthol, Camphor

Question 20

Pruritis tx; TRPV1 agonist

Answer 20

Capsaicin

Question 21

Ectoparasite drug that inhibits Acytlcholinesterase

Answer 21

Malathion

PML
NAG

Question 22

Ectoparasite drug that binds Na channels

Answer 22

Permethrin

PML
NAG

Question 23

Ectoparasite drug that inhibits GABA transmission

Answer 23

Lindane

PML
NAG

Question 24

Ectoparasite drug that binds glutamate-gated Cl channels

Answer 24

Ivermectin

Question 25

Topical retinoid used for acne

Answer 25

Tretinoin

Question 26

Topical antimicrobials used for acne

Answer 26

benzoyl peroxide, clindamycin, erythromycin

Question 27

Plant based antibacterial

Answer 27

Azaleic acid

Question 28

Oral retinoid used for acne

Answer 28

isoretinoin

*teratogen!!!

Question 29

Initial tx for mild to moderate psoriasis

Answer 29

Emollients and corticosteroids

Question 30

PDE4 inhibitor used to treat psoriasis

Answer 30

Apremilast

PDE4 inhibition -> decreased inflammatory markers

Question 31

Monoclonal Ab against IL-12 and IL-23 used to treat psoriasis

Answer 31

Ustekinumab

u 12 23

Question 32

Monoclonal Ab against IL-17 used to treat psoriasis

Answer 32

Secukinumab

sec 17

Question 33

Thymidylate synthase inhibitor used to treat actinic keratosis

Answer 33

topical 5-fluorouracil

Question 34

Immune response modifier that causes infiltration of inflammatory cells to treat actinic keratosis

Answer 34

Imiquimod

Question 35

Hedgehog pathway inhibitors used to treat advanced BCC

Answer 35

vismodegib, sonidegib

-degib

Question 36

Chemotherapeutic agent used for melanoma

Answer 36

Dacarbazine

Question 37

BRAF V600E inhibitor used to treat melanoma

Answer 37

Vemurafenib

Question 38

Vasodilator used for male pattern baldness

Answer 38

Minoxidil

Question 39

5a-reductase inhibitor used to treat male pattern baldness

Answer 39

Finasteride

Question 40

treatment for alopecia areata (immune mediated)

Answer 40

DPCP (contact dermatits that causes hair growth)