derm - Cytology and Biopsy of Tumors

Question 1

Surgical Pathology report components

Answer 1

Description
 Make sure you read and understand this part.
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Diagnosis (or diagnostic hypothesis!)
 Look for ‘probability of certainty’ of diagnosis
 ‘Slam dunk’- specific diagnosis
 ‘Compatible’, ‘Consistent’, Generic tumor type (round cell, mesenchymal cell)
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Comments
 Should provide prognosis in terms of probability
> Statistical information on clinical outcome: – not ‘malignant’, ‘poor prognosis’
> Metastatic rate, Progression free interval, Disease free interval, 12 and 24 month survival,
> Median survival is problematic.

Question 2

What you expect for neoplasms….

Answer 2

 Diagnosis
 Prognosis
 Margins

Question 3

Diagnosis of neoplasms
- importance
- naming convention

Answer 3

 Most important to determine prognosis.
 Name based on phenotype (what the cells look like or
express)
 Usually reflects ‘cell of origin’
 Based on latest Fascicles and consensus papers.
 Choose your preferred pathologist!

Question 4

Diagnostic approach to Skin Masses

Answer 4

Know what you are dealing with…
 Location of the mass in relationship to important structures.
 Cytology
 Surgical dose – compartment and barriers
 Histopathology
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Neoplastic
 Epithelial
 Mesenchymal
 Round cell
 Other
> melanoma
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Non-neoplastic