Derm Flashcards
First-line management for hyperhidrosis?
Topical aluminium chloride
Most accurate way of measuring TBSA for burns?
Lund and Browder chart
Wallace’s rule of Nines
head + neck = 9% each arm = 9% each anterior leg = 9% each posterior leg = 9% anterior abdomen = 9% posterior abdomen = 9%
Note: not accurate > 15% TBSA
TBSA of palmar surface?
1%
When would you refer burns to secondary care? (6)
- all deep dermal and full-thickness burns.
- superficial dermal burns of more than 3% TBSA in adults, or more than 2% TBSA in children
- superficial dermal burns involving the face, hands, feet, perineum, genitalia, or any flexure, or circumferential burns of the limbs, torso, or neck
- any inhalation injury
- any electrical or chemical burn injury
- suspicion of non-accidental injury
Which rash is commonly associated with HSV?
Erythema multiforme
Which drugs cause erythema multiforme?
penicillin sulphonamides carbamazepine allopurinol NSAIDs oral contraceptive pill
Which drug can exacerbate psoriasis?
Lithium
Initial management of actinic keratoses?
Topical fluorouracil cream
Strep throat then rash 2-4 weeks later?
Guttate psoriasis
Appearance of pityriasis rosea v. guttate psoriasis?
PR –> herald-patch then fir tree, erythematous + scaly lesions
GP –> ‘tear drop’ papules on trunk + limbs
When should IV fluids be given for burns?
Second/third degree > 15% (superficial dermal + partial thickness or more)
Eczema herpeticum - management
Hospital for IV acyclovir
Lichenoid drug eruptions caused by?
gold
quinine
thiazides
Lichen planus - initial management?
Topical steroids
Seborrheic dermatitis - first-line management?
OTC preparations containing zinc pyrithione + tar
Rash - hypopigmented and more obvious after sun tanning
Pityriasis versicolor
Formula to calculate volume of IV fluids needed in first 24 hour in burns?
Parkland formula
Skin manifestations of SLE
photosensitive ‘butterfly’ rash
discoid lupus
alopecia
livedo reticularis: net-like rash
Well-demarcated patch marks of hair loss in younger woman with peripheral “exclamation point” short broken hairs
Alopecia areata
Lesion initially a smooth dome-shaped papule –> rapidly grows to become a crater centrally-filled with keratin
Diagnosis?
Keratoacanthoma
Lichen sclerosus - initial management
topical clobetasol propionate
Sounds like acne but wrong age group
Acne rosacea
Acne rosacea, mild/moderate - management?
Topical metronidazole
Acne rosacea, severe/resistant - management?
Oral tetracycline
Bullous pemphigoid - management?
Oral corticosteroids
Squamous cell carcinoma in an area with chronic inflammation?
Marjolin’s ulcer
Which derm cancer has increased risk in immunocompromised?
SCC
Young girl (17) with lanugo - common cause?
Malnutrition
Burns –> haematemesis + Shock
Curling’s ulcer
Severe hirsutism - management?
co-cyprindiol
Erythema multiforme + mucosal involvement?
Erythema multiforme major
What are the skin appendages?
Hair follicle, sebaceous gland, apocrine / eccrine sweat glands, nail
What comprises the pilosebaceous unit?
Hair follicle, sebaceous gland, arrector pili muscle
What cells are found in the epidermis?
Keratinocytes, melanocytes, Langerhans cells, Merkel cells
Psoriasis is unresponsive to conventional treatment - next step of management?
Topical retinoids
Causes of onycholysis
Skin disease Systemic disease Infection Trauma Idiopathic
What is koilonychia?
Spooning of nails, seen in IDA
Which drug can cause generalised alopecia?
Warfarin
What type of HS is contact dermatitis?
Type IV
Causes of pyoderma gangrenosum?
UC + Crohn’s
RA
Idiopathic
Management of pyoderma gangrenosum?
High dose steroids
Non-adherent dressings
What condition is associated with lupus pernio?
Sarcoidosis
What is pellagra?
From deficiency of B3 (niacin/nicotinic acid)
Dermatitis, diarrhoea, dementia
‘apple jelly’ nodules
lupus vulgaris
cutaneous manifestation of TB
Cause of molluscum contagiosum?
Pox virus
Buzzwords - violaceous, polygonal, popular eruption on flexor aspects
Lichen planus
Function of Apo C-II?
Co-factor of lipoprotein lipase
Function of lipoprotein lipase?
Hydrolyses triglyceride in chylomicrons and VLDLs
Consequence of apo C-II deficiency?
elevated chylomicrons and VLDL
Bullous pemphigoid affects:
desmosome hemidesmosome zonula occludens zonula adherens gap junction
hemidesmosome
Pemphigus vulgaris affects:
desmosome hemidesmosome zonula occludens zonula adherens gap junction
desmosome
Erythematous rash on face + telangiectasia?
Pityriasis rosea