Derm Flashcards
Basal cell tumors
Arise from basal layer of epidermis
Occur most commonly on the head or neck of cats
Can be cystic or pigmented
Virus-induced papillomas
Most often spontaneously regress
Occur most often in young, purebred dogs
Can occur in older, immunosuppressed dogs
Multicentric squamous cll carcinoma insitu (Bowen’s disease)
Occurs most often in older cats
Lesions appear as plaques or papillation with scale
Associated with chronic papillomavirus infection
NOT associated with UV light
Which neoplasm is associated with actinic dermatitis in dogs?
SCC
What clinical findings are suggestive of actinic dermatitis?
Erythema
Scale
Comedones
Non-healing ulcers and erosions
Cats develop which follicular origin tumors?
Trichoblastoma
Differentials for nail bed/subungual tumors?
SCC
Malignant melanoma
Keratocanthoma
Two common neoplasms occurring on eyelid of dogs
Meibomian gland adenoma
Melanocytoma
Hepatoid neoplasms
Androgen dependent
Most often adenomas (benign)
Found on the perianal skin, prepuce, or tail
Anal sac neoplasms
Most often adenocarcinomas
Can be associated with hypercalcemia of malignancy
Rarely cured by excision
T/F? In cats, melanocytic tumors occurring on the haired skin are more often malignant when compared to the dog
False
Biological behavior of soft tissue sarcomas
Locally invasive
Low potential for metastasis
Recurrent with incomplete excision
Feline vaccine associated tumors
Include a a wide variety of sarcomas
Are uniformly locally aggressive and recurrent
Can be accurately identified by histological features that include lymphocytic aggregates and macrophages containing foreign material
Feline abdominal lymphangiosarcoma
Clinically appers as a diffuse area of swelling, bruising along the bentral abdomen
Is virtually impossible to resect
Carriesa very poor prognosis for survivial
Perivascular wall tumors (PWT) in dogs
Include a number of variably differentiated mesenchymal tumors such as hemangiopericytomas
Often occur on the limb
Are locally aggressive and highly recurrent
Dermal hemangiosarcoma
Occurs with higher incidences in Whippets and Italian Greyhounds
Occur most often in sun exposed, lightly pigmented, thinly hIRED SKIN
DO NOT DEVELOP FROM HEMANGIOMAS BUT ARE THOUGHT TO ARISE DE NOVO
Cutaneous mass cell tumors in the dog
Have a highly variable clinical appearance
Are routinely assigned a histological grade used to help predict biological behavior
Have a highly degree of unpredictability if they are of intermediate differentiation
Cutaneous mast cell tumors in the cat
Are not associated with splenic mast cell disease
Have no accepted grading system
Have a very low potential for malignancy and are often considered curable by excision
Solitary cutaneous plasma cell tumor in the dog
Are not associated with multiple myeloma
Occur most often on the pinna, in the ear canal, or the rectum or mouth
Can have a very pleomorphic histological appearance but are benign and cured by excision
Cutaneous epitheliotropic lymphoma in dogs and cats
Present with erosions and ulcers in the oral cavity about 40% of the time
Is of T lymphocyte origin
Typically presents with alopecic, exfoliative, erythematous lesions with or without plaques or nodules
Histiocytic neoplasms and reactive proliferation of histiocytic cells occur most often in
Dogs
Solitary cutaneous histiocytomas in the dog
Are proliferation of non-neoplastic intraepidermal dendritic cells (langerhans cells)
Occur most odten in young dogs on the head, pinna, feet, or scrotum
Regress spontaneously if left alone
Canine cutaneous reactive histiocytosis is characterized by
Clinically by nodules and plaques
Waxing and waning of lesions
Histologically by sheets of large histiocytic cells mixed with other leukocytes
Canine systemic histiocytosis
Has clinical and histological features that overlap with cutaneous reactive histiocytosis
Has multi organ involvement and is progressive and fatal disease
Occurs most often in Bernese Mountain Dogs, Goldens, Labs, Dobies, Rottweiler
Disseminated histiocytic sarcoma
Malignancy of histiocytic dendritic cells
Was previously called malignant histiocytosis
Is a multisytemic fatal disease often involving the spleen, liver, LN , and lung
Feline Lung Digit Syndrome
Unusual tendency of primary lung carcinomas in cats to metastasize to the digits
Differentials for nodular spleen
Systemic histiocytosis
Malignant histiocytosis/disseminated histiocytic sarcoma
Malignant fibrous histiocytoma
Localized histiocytic sarcoma
