Derm Flashcards

1
Q

Multiple skin tag association?

A

Insulin resistance, Crohn (perianal), Pregnancy

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2
Q

Severe seborrheic dermatitis association?

A

Parkinsons, HIV

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3
Q

Pyoderma gangrenosum association?

A

IBD

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4
Q

Explosive onset of multiple itchy seborrheic keratosis?

A

GI malignancy

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5
Q

Tx of acne vulgaris?

A

Comedonal-topical retinoids/salicylic acid
Inflammatory-topical abx/oral abx
Nodular (cystic)-oral abx/oral isotretinoin

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6
Q

Tx rosacea?

A

Metronidazole

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7
Q

Sunscreen protocol?

A

30 minutes before exposure SPF15-30 or higher and reapplied at least every 2 hours

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8
Q

Tx of limited vs diffuse impetigo

A

Limited-topical abx (mupirocin)

Extensive-oral abx (cephalexin, dicloxacillin, clindamycin)

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9
Q

Erysipelas cause vs. Cellulitis (purulent and nonpurulent cause)

A

Erysipelas-S pyogenes

Cellulitis (purulent vs nonpurulent)-S aureus vs streptococci

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10
Q

1st and 2nd line tx for tinea corporis?

A

1st line-topical antifungals (eg clotrimazole, terbinafine)

2nd line-oral antifungals (eg terbinafine, griseofulvin)

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11
Q

Tinea versicolor bacteria tx?

A

Malassezia. Topical ketoconazole, terbinafine, or selenium sulfide

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12
Q

Tinea capitis management?

A

Oral griseofulvin (1st line), terbinafine, itraconazole, or fluconazole

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13
Q

Common antipsychotic to have photosensitivity rxn?

A

Chlorpromazine or prochlorperazine-both typical antipsychotics

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14
Q

Common diuretic to cause photosensitivity?

A

Furosemide or HCTZ

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15
Q

Scabieslice (pediculosis) tx?

A

Permethrin cream to whole body

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16
Q

Lichen planus diagnosis?

A

Pruritic, purble, polyglonal papules on wrists and lower legs

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17
Q

What should be in differential for piyriasis rosea?

18
Q

Classic erythema nodosum on USMLE?

A

Sarcoid coccidio or Ulcerative colitis

19
Q

Pemphigus vulgaris presentation?

A

IgG to desmoglein (part of desmosomes). tx. oral corticosteroids. nikolsky+, oral mucosa involved. Net like fluorescent imaging

20
Q

Bullous pemphigoid presentation?

A

IgG to hemidesmosomes (subepithelial). tx topical steroid (clobetasol). nikolsky - and no oral mucosa. linear immunofluorescence

21
Q

What determines if lesion should be excised with 1 cm tumor free margin or have lymph node biopsy study?

A

less than or greater than 1 mm depth

22
Q

Management of widespread melanoma?

A

surgical removal

23
Q

2 serious risk factors of SCC?

A

1) Long term immunosuppression/transplant patient

2) Sunlingt or wounded/scarred/inflammed skin (skin overlying osteo or radiotherapy or venous ulcers)

24
Q

What type of AIDS is only associated with Kaposi sarcoma?

A

Sexual contact

25
Tx kaposi
1) tx aids 2) tx vincristine and interferon 3) chemo with liposomal doxorubicin
26
Medical tx actinic keratosos?
5-FU topical or imiquimod topical
27
What drugs can be used to help patients get off topical steroids in atopic dermatitis?
Tacrolimus/sirolimus
28
What drugs can be used to help patients get off topical steroids in psoriasis?
Vitamin A and D derivatives. Vitamin D agent is calcipotriene.
29
Tx extensive psoriasis?
UV light, anti TNF, methotrexate
30
Tx pityriasis rosea
UV light and steroids
31
Cause and systematic treatment scheme of pemphigus vulgaris?
- ACEi, Penicillamine, Phenobarbital, Penicillin | - Oral steroids, azathioprine and mycophenalate to wean off, rituximab and IVIG refractory cases
32
Tx bullous pemphigoid?
ral steroids, azathioprine and mycophenalate and cyclophosphamide to wean
33
Most accurate test PCT?
24 hour uroporphyrin increase in urine
34
Impetigo tx with mild, severe, and community acquired MRSA?
Mild-mupirocin, retapamulin, bacitracin topical Severe-cephalexin or dicloxacillin oral Comm acquired MRSA-doxy, clinda, TMPSMZ
35
Treatment of all skin infections (erysipeals, cellulits, folliculitis etc) similar. What is mild vs severe?
Mild (oral)-dicloxacillin, cephalexin. Penicillin allergic with erythromycin, clarithromycin or clindamycin. MRSA with doxy, clinda, TMPSMX Severe (IV)-oxacillin, nafcillin, cefazolin, penicillin allergic with clinda and vancomycin. MRSA with vanco linezolid, tigecycline or ceftaroloine (only cephalosporin for mrsa)
36
What are antistaphylococcal penicillins?
Ox-clox-diclox-naf
37
Best initial/most accurate tinea?
Best initial-KOH prep | Most accurate-Fungal culture
38
Oral and vaginal candidiasis best initial and most accurate?
Best initial-KOH prep and Most accurate: Fungal culture
39
Drug causing hypersensitivity reactions?
Penicillins, sulfa drugs (thiazides, furosemide, and sulfonylureas), allopurinol, phenytoin, lamotrigine, NSAIDs. Rmr Hypersensitivity of skin (erythema multiforme, SJS, TEN) is same as hemolysis, interstitial nephritis, and often drug induced thrombocytopenia
40
Tx of dermatitis herpetiformis?
Dapsone