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Step 2 CK > Derm > Flashcards

Derm Flashcards

1
Q

Multiple skin tag association?

A

Insulin resistance, Crohn (perianal), Pregnancy

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2
Q

Severe seborrheic dermatitis association?

A

Parkinsons, HIV

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3
Q

Pyoderma gangrenosum association?

A

IBD

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4
Q

Explosive onset of multiple itchy seborrheic keratosis?

A

GI malignancy

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5
Q

Tx of acne vulgaris?

A

Comedonal-topical retinoids/salicylic acid
Inflammatory-topical abx/oral abx
Nodular (cystic)-oral abx/oral isotretinoin

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6
Q

Tx rosacea?

A

Metronidazole

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7
Q

Sunscreen protocol?

A

30 minutes before exposure SPF15-30 or higher and reapplied at least every 2 hours

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8
Q

Tx of limited vs diffuse impetigo

A

Limited-topical abx (mupirocin)

Extensive-oral abx (cephalexin, dicloxacillin, clindamycin)

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9
Q

Erysipelas cause vs. Cellulitis (purulent and nonpurulent cause)

A

Erysipelas-S pyogenes

Cellulitis (purulent vs nonpurulent)-S aureus vs streptococci

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10
Q

1st and 2nd line tx for tinea corporis?

A

1st line-topical antifungals (eg clotrimazole, terbinafine)

2nd line-oral antifungals (eg terbinafine, griseofulvin)

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11
Q

Tinea versicolor bacteria tx?

A

Malassezia. Topical ketoconazole, terbinafine, or selenium sulfide

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12
Q

Tinea capitis management?

A

Oral griseofulvin (1st line), terbinafine, itraconazole, or fluconazole

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13
Q

Common antipsychotic to have photosensitivity rxn?

A

Chlorpromazine or prochlorperazine-both typical antipsychotics

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14
Q

Common diuretic to cause photosensitivity?

A

Furosemide or HCTZ

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15
Q

Scabieslice (pediculosis) tx?

A

Permethrin cream to whole body

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16
Q

Lichen planus diagnosis?

A

Pruritic, purble, polyglonal papules on wrists and lower legs

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17
Q

What should be in differential for piyriasis rosea?

A

Syphilis

18
Q

Classic erythema nodosum on USMLE?

A

Sarcoid coccidio or Ulcerative colitis

19
Q

Pemphigus vulgaris presentation?

A

IgG to desmoglein (part of desmosomes). tx. oral corticosteroids. nikolsky+, oral mucosa involved. Net like fluorescent imaging

20
Q

Bullous pemphigoid presentation?

A

IgG to hemidesmosomes (subepithelial). tx topical steroid (clobetasol). nikolsky - and no oral mucosa. linear immunofluorescence

21
Q

What determines if lesion should be excised with 1 cm tumor free margin or have lymph node biopsy study?

A

less than or greater than 1 mm depth

22
Q

Management of widespread melanoma?

A

surgical removal

23
Q

2 serious risk factors of SCC?

A

1) Long term immunosuppression/transplant patient

2) Sunlingt or wounded/scarred/inflammed skin (skin overlying osteo or radiotherapy or venous ulcers)

24
Q

What type of AIDS is only associated with Kaposi sarcoma?

A

Sexual contact

25
Q

Tx kaposi

A

1) tx aids
2) tx vincristine and interferon
3) chemo with liposomal doxorubicin

26
Q

Medical tx actinic keratosos?

A

5-FU topical or imiquimod topical

27
Q

What drugs can be used to help patients get off topical steroids in atopic dermatitis?

A

Tacrolimus/sirolimus

28
Q

What drugs can be used to help patients get off topical steroids in psoriasis?

A

Vitamin A and D derivatives. Vitamin D agent is calcipotriene.

29
Q

Tx extensive psoriasis?

A

UV light, anti TNF, methotrexate

30
Q

Tx pityriasis rosea

A

UV light and steroids

31
Q

Cause and systematic treatment scheme of pemphigus vulgaris?

A
  • ACEi, Penicillamine, Phenobarbital, Penicillin

- Oral steroids, azathioprine and mycophenalate to wean off, rituximab and IVIG refractory cases

32
Q

Tx bullous pemphigoid?

A

ral steroids, azathioprine and mycophenalate and cyclophosphamide to wean

33
Q

Most accurate test PCT?

A

24 hour uroporphyrin increase in urine

34
Q

Impetigo tx with mild, severe, and community acquired MRSA?

A

Mild-mupirocin, retapamulin, bacitracin topical
Severe-cephalexin or dicloxacillin oral
Comm acquired MRSA-doxy, clinda, TMPSMZ

35
Q

Treatment of all skin infections (erysipeals, cellulits, folliculitis etc) similar. What is mild vs severe?

A

Mild (oral)-dicloxacillin, cephalexin. Penicillin allergic with erythromycin, clarithromycin or clindamycin. MRSA with doxy, clinda, TMPSMX
Severe (IV)-oxacillin, nafcillin, cefazolin, penicillin allergic with clinda and vancomycin. MRSA with vanco linezolid, tigecycline or ceftaroloine (only cephalosporin for mrsa)

36
Q

What are antistaphylococcal penicillins?

A

Ox-clox-diclox-naf

37
Q

Best initial/most accurate tinea?

A

Best initial-KOH prep

Most accurate-Fungal culture

38
Q

Oral and vaginal candidiasis best initial and most accurate?

A

Best initial-KOH prep and Most accurate: Fungal culture

39
Q

Drug causing hypersensitivity reactions?

A

Penicillins, sulfa drugs (thiazides, furosemide, and sulfonylureas), allopurinol, phenytoin, lamotrigine, NSAIDs. Rmr Hypersensitivity of skin (erythema multiforme, SJS, TEN) is same as hemolysis, interstitial nephritis, and often drug induced thrombocytopenia

40
Q

Tx of dermatitis herpetiformis?

A

Dapsone

Step 2 CK (16 decks)

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