Depression Flashcards

1
Q

Define euthymic

A

Normal mood

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2
Q

Define hyperthymic

A

Elevated mood

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3
Q

What is the name given to variable mood?

A

Cyclothymic

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4
Q

What is the name given to an extrovert?

A

Sanguine

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5
Q

Define malancholic

A

Perfectionist, worrier

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6
Q

What is the name given to someone who is self-content, kind?

A

Phlegmatic

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7
Q

What is the name given to leaders in charge?

A

Choleric

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8
Q

State the name given to loss of enjoyment/pleasure

A

Anhedonia

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9
Q

What does anergia mean?

A

Lack of energy

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10
Q

What is the name given to lack of motivation?

A

Amotivation

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11
Q

What term is used to describe mood that varies over the day?

A

Diurnal variation

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12
Q

What is classed as early morning wakening?

A

2 hours before normal waking time

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13
Q

Define psychomotor retardation

A

Subjective/objective slowing of thoughts and movements

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14
Q

Define stupor

A

Absence of relational functions

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15
Q

In depression what will the patients appearance and behaviour look like?

A

Reduced facial expression, frowning, reduced eye contact, limited gesturing, difficult to establish rapport

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16
Q

What can be observed in the speech of a depressed patient?

A

Slow, lower pitch, reduced volume, monotonous, increased latencies - longer time between question and answer, limited content (short and brief)

17
Q

How will mood and affect appear in depressed patients?

A

Mood - low, down, miserable, sad, unhappy, flat, empty

Affect - depressed, reduced range and limited reactivity may report emotional paralysis

18
Q

What are the findings in depressed patients - form, flow and content of thought?

A

Form - normal
Flow - slowed, pondering or even absent
Content - negative, self-accusatory, guilt, pessimism
Suicidal thoughts and delusions can occur

19
Q

What themes of delusions may occur in depression?

A

Guilt, poverty, nihilism, hypochondriasis

20
Q

Describe the perception in depressed patients

A

Mainly normal, increased feeling of people looking/talking about them

21
Q

What hallucinations are more likely in depression?

A

Auditory second person reflect negative themes - derogatory

22
Q

Describe the cognition in a depressed patient

A

Subjectively slow with poor memory, pseudo-dementia can occur compounded by anxiety

23
Q

Describe the insight in a depressed patient

A

Typically preserved, aware of symptoms and abnormalities. Attribution often affected and blame their symptoms on past actions

24
Q

What is the general criteria for depression?

A

Episode should last at least two weeks with no hypomania or manic symptoms at any time in the patients life

25
What are the three core features of depression? How many do you need for diagnosis?
- depressed mood most days for most of the day - loss of interest or pleasure - decreased energy/increased fatigue 2 required for diagnosis
26
What are the additional symptoms of depression and how many are needed for diagnosis?
- loss of confidence - feelings of guilt - suicidal thoughts - concentration difficulties - psychomotor activity (agitation or retardation) - sleep disturbance - change in appetite/weight
27
Define moderate depression
Two core features plus four additional = total of 5- 6
28
Define severe depression
All three core features plus five additional = total of 8 /(>7)
29
What is psychotic depression?
Paranoid, mood congruent or hypochondriacal, worry more, deserve disease due to past actions
30
What is cotards syndrome?
Nihilistic delusions, more common in elderly and often very extreme
31
Define dysthymia
Chronic depression present for 2 years
32
What is first line treatment for depression?
CBT - mild | SSRI - moderate/severe
33
Other than SSRI what other drugs can be used?
Atypical (second line) SNRI Tricyclics
34
What does chronic stress lead to?
Cortisol dysregulation and impairment of the HPA axis
35
What area of the brain is particularly susceptible to damage from cortisol?
Hypocampus
36
What process allows medications in depression to be effective?
Increased MAO-A activity which reduced monoamines circulating