Depression Flashcards

1
Q

WHat are the symptoms?

A
  • Cognitive : trouble concentrating and making decisions
  • behavioural: social withdrawal
  • somatic (physical) - insomnia/ hypersomnia
  • affective - sad
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2
Q

what are the subtypes

A

reactive
endogenous
unipolar
bipolar

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3
Q

gentics

A

60% monozygotic

15% disygotic

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4
Q

Brown - environment

A

84% of depressed patients had experienced stress in the previous year
32% of the control also had severe stress in previous year but no depression.

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5
Q

What is the primary model of depression

A

The diathesis stress model

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6
Q

how do MAOI’s work

A

They break down the enzyme which breaks down monamine neurotransmission which results in more neurotransmitters in the synapse.

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7
Q

What are tricyclic antidepressants?

A

They slow the rate of re uptake of serotonin and norephinphrine.
But unwanted side effects - weight gain, dry mouth, constipation, drowsiness and dizziness.

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8
Q

What are monamines ?

A

Epinephrine, norepinephrine and serotonin

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9
Q

What are SSRIs

A

more selective that TCAs, they mainly work on serotonin.

a type of SSRI is prozac

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10
Q

What is used to treat bipolar

A

lithium.

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11
Q

Theories of depression

A

antidepressants act on monamines therefore depression results from a deficit in monamine neurotransmitters : Serotonin, norephinephrine and epinephrine.

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