Depression Flashcards

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0
Q

List the symptoms of depression

A

Anhedonia

Grief

Guilt

Self injury (suicide)

Psycho motor retardation

Vegetative symptoms

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1
Q

List the two types of depression

A

Reactive depression-specific event, days or weeks

Maj. Depression-may or may not have a specific event associated with it, last longer can be weeks or months

These two kinds can be related

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2
Q

What does anhedonia mean

A

Inability to feel pleasure

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3
Q

Explain psychomotor retardation

A

When the thoughts of doing anything is exhausting or too much to handle

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4
Q

Explain vegetative symptoms associated with depression

A

Sleep patterns disrupted (specifically early morning waking)

Appetite decreased usually

Activation of stress response

Over activation of the sympathetic nervous system releasing stress hormones

Increased metabolic rate

Increased muscle tone

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5
Q

List the neurotransmitters involved in depression

A
Neriepinephrine 
dopamine 
serotonin
 substance P 
acetylcholine
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6
Q

Explain noriepinephrine effects as related to depression

A

Effects psychomotor retardation (and may also be involved in a reward pathway)

MAO inhibitors-inhibit the enzyme that degrades neroepinephrine

Trycyclic antidepressants-inhibit norepinephrine recycling

Different classes of drugs that inhibit euro epinephrine release-(hypertension drugs) cause depression as a side effect

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7
Q

What does dopamine effect in relation to depression

A

Anhedonia

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8
Q

What to serotonin affect in relation to depression

A

Grief and guilt

Prozac (SSRI)

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9
Q

What does substance P do?

A

It’s involved in the pain response

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10
Q

What does acetylcholine effect in regard to depression

A

Acetylcholine affects sleep patterns with Neroepinephrine

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11
Q

What does the reptilian brain do

A

Keeps body functioning

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12
Q

What does the limbic system do

A

Emotional response

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13
Q

What does the cortex do

A

Executive functions

Abstract thought

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14
Q

What was the main take away point from the Stanford lecture about the parts of the brain and which one is responsible for depression

A

The cortex whisper sad thoughts and gets the rest of the brain to go along with it

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15
Q

What hormones are thought to be responsible for 20% of depression

A

Thyroid hormones

Hypothyroidism

16
Q

List main points of hormones influence with depression

A

Thyroid-hypothyroidism approximately 20%

Women are at higher risk

Risk highest-six months after giving birth

Menopause

Time of menstruation

17
Q

Explain the process involved in stress hormones being released in regard to depression

A

HPA-axis

Normal process-

Hypothalamus communicates by releasing corticotropin releasing hormone

Anterior pituitary releases adrenocorticotropic

Adrenal gland releases cortisol (which feeds back into the hypothalamus in interior pituitary to tell them to stop producing because there is enough cortisol)

This event happens whenever stressful events happen (people with depression tend to have higher levels of cortisol)