Addiction Flashcards
What do opiates do
Work on endorphins
Large releases of dopamine
Explain the different ways drugs can work
They can increased levels of natural neurotransmitters
Increase of dopamine-remember this event
Opiates (and meth release dopamine)
Cocaine-blocks the reabsorption of dopamine and neroepinephrine
Mimic the activity of neurotransmitters-
Nicotine-acetylcholine
Alcohol-binds to the acetylcholine and serotonine receptors
Explain the pathophysiology to tolerance (List the different ways tolerance can happen)
Increase in number of receptors-example large amounts of nicotine in the body will increase the amount of acetylcholine receptors-so when nicotine levels decrease the body exhibit symptoms of withdrawal
Increase the release of excitatory neurotransmitter’s-example alcohol trying to balance the system
Increase dopamine degrading enzyme
Depletion of neurotransmitters
