dentin Flashcards

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1
Q

dentin formation begins when in development and by what

A

early in bell stage - develops from tooth apex down slopes of cusps : coronal dentin (root dentin later)

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2
Q

dentinogenesis

A

by odontoblasts (cells) that differentiate from ectomesenchymal cells from the dental papilla (odontogenesis)

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3
Q

Dentin phospoprotein (DPP)

A

most acidic non - collagenous protein and is Ca2+ binding.

these NCP’s are regulating dentin mineralization and secreted by the odontoblast processes

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4
Q

intermediate dentin aka

A

peritubular dentin

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5
Q

why can caries progress faster in dentin?

A

half the mineral as enamel and twixe the carbonate and fraction of crystallite size
calcium deficient / carbonate -rich defective apetite
NOT PURE HAP
highly soluble in acids

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6
Q

interglobular dentin

A

just beneath the mantle dentin where

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7
Q

DSPP mutations cause which diseases?

A

DD-II, DGI-II and DGI-III

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