Dementia Flashcards
dementia definition
progressive decline (2/6 domains)
what are the domains
- memory
- language
- social cognition
- attention
- executive function
- perceptial motor
Alzheimer’s disease
- age over 40
- early memory loss
- dementia (2 domains)
- no other medical condition
non cognitive symptoms of AD
apathy hallucinations, depression, agitation, sleep issues
tx for AD
- cholinesterase inhibitors
- NMDA recetpr antag
- CBT
- SSRI, AED
- education
cholinesterase inhibitos
donepezil, rivastigmine, galantamine
NMDA recetor antag
memantine
AD neuroimaging
PET- low temporal and peraietal uptake
MRI- temporal lobe atrophy with horns are quite larhe
microscopic findings of AD
phosphorylated tau tangles and
criteria for FTD
at least 3 of
- executive dysfunction
- apathy
- change in diet
- compulsive repetitive behavior
- loss of sympathy/empathy
- behavioral disinhibtiom
FTD micro
picks bodies (stains for tau)
vascular dementia criteria
CVD
>2 domains
-onset of dementia within 3 months, abrupt deterioration, stepwise fluctuations
treatment for vascular deentia
same as AD (anticholinesterase and NMDA recet=ptro antagonist)
parkinson’s disease dementia
develops after patient has PD for 5-7 years
criteria:
-bradyphenia, depression, reiterative speech, EDF
dementia with ley bodies
- dementia
- prominent memory loss
- deficits attention, EF, visuospatial
- REM sleep disorder
- spontaneous parkinsonism
- -halluncinations
