Acute and Chronic Childhood Neurologic Disorders Flashcards

1
Q

CSF findings in bacterial meningitis

A

Protein high, glucose low, WBC (neutrophils)

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2
Q

Infancy meningitis

A

listeria, e coli, group B strep

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3
Q

child to adult meningitis

A

H flu, strep pneumo, neisseria

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4
Q

ADEM (acute disseminated encephalitis) etiology

A

post-infectious

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5
Q

ADEM (acute disseminated encephalitis) what do you see

A

both gray and white matter lesions in brain and spinal cord

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6
Q

Transverse myelitis

A

only in the spinal cord but both in the white and gray matter

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7
Q

how to differentiate Transverse myelitis from MS

A

multiple levels of the spine have lesions

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8
Q

Acite cerebellar ataxia (what is it)

A

begins at age 2-4 and is thought to be after VZV with ataxia with explosive onset

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9
Q

treatment for acute cerebellar ataxia

A

self-limited

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10
Q

GBS- LP

A

cytoalbuminic dissociation

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11
Q

two variants of GBS

A

miller-fisher (face and weakness) bickerstaff (seizure and conscioussness)

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12
Q

Botulinum clinical presentation

A

descending paralysis (face and lungs) with constipation as first symptom

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13
Q

list disorders causing early developmental delay

A

Down, cerebral palsy, NTD, metabolic and brain malformation

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14
Q

types of cerebral palsy

A

spastic, hypotonic, dyskinestic

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15
Q

lissencephaly

A

no gyri in the brain

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16
Q

schizencephaly and porencephaly

A

brain tissue doesnt develop

17
Q

chiari 1 2 3

A

1- cerebellar tonsilar herniation
2- meningomyelocele and hydrocephalus
3- occiptal encephalocele

18
Q

rett syndrome

A

girls only (X linked), autistic behavior at 1-3y/o, microcephaly and purposeless hand movement

19
Q

fragile x variant

A

FXTAS- pre-mutation Fragile X tremor and ataxia syndrome (at 50 y/o)

20
Q

global developmental delay definition

A

at least 2 of following (gross motor, fine motor, social and speech)

21
Q
neurodegenerative disorder: name the disorder
cerebral
basal ganglia
cerebellum
spinal cord
nerve
muscle
A
rett syndrome
PKAN
friedrich's ataxia
familial spatic paraplegia
spinal muscle atrophy
duchenne muscular dystrophy
22
Q

best testing for duchenne’s

A

CK elevated above 10K

23
Q
autoimmune disorders- name the disorder
cerebral
brainstem
cerebellum
spinal cord
nerve
muscle
A
ADEM
ADEM
acute cerbellar ataxia
transverse myelitis
guillain barree
dermatomyosisitis
24
Q

sturge weber - clinica presentation

A

CN V
port wine stain
glaucoma

25
Q

NF1

A
cafe au lait
inguinal/axial freckling
neurofibroma
bony malformations
lisch nodules
optic gliomas
26
Q

Tuberous sclerosis

A
tubers (cortical)
subependyma nodules
subependymal giant cell astrocytoma
seizures
developmental  delay
hypomelanotic macules (ash leaf spot)
shagreed spot