Delirium/Dementia Flashcards
What is considered an “Abnormal” score on a Mini Mental Status Exam (MMSE)
<24
What MMSE indicates increased odds of dementia? What level of education is this?
<21
Abnormal for 8th grade education
What MMSE range is considered NO cognitive impairment?
24-30
What is the risk of death in hospitals associated with delirium?
10 fold risk
List the 3-5 fold increased risks associated with delirium (other than death)
- Nosocomial complications
- Prolonged stay
- Post-acute NH placement
How long following discharge are patients at an increased risk for poor functional recovery and increased risk of death following their delirium?
2 years
What % of delirium is recognized by nurses? by physicians?
Nurses=50%
MD’s=20%
Clinically, what do we use to diagnose delirium?
Confusion Assessment Method (CAM)= 95% sensitivity and specificity
What is the MC type of delirium
HYPOactive delirium=50%
What is the other type of delirium? %?
HYPERactive delirium=25%
What type of delirium has a poorer prognosis ? Why?
HYPOactive delirium:
- Less recognized
- Not appropriate tx
List the two Neuropathophysiology causes for delirium
- Cholinergic deficiency
2. Inflammation
Delirium Etiology in cholinergic deficiency? Treatment?
Anticholinergic Drug OD
Tx: Physostigmine
What increases with inflammation associated delirium?
- C-Reactie Protein
- IL-1B
- TNF
What patients does inflammation delirium especially affect?
- Postop pt’s
- CA pt’s
- Sepsis pt’s