Definitions Flashcards

1
Q

Cardiotonic agents

A

Drugs increasing strength of myocardial contractions in acute or chronic heart failure

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2
Q

Heart failure

A

Reduction of myocardial contractile function (decompensation). HF leads to the inability of the circulatory system to deliver the necessary amount of blood to organs and tissues.

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3
Q

Antiarrhythmic drugs

A

Drugs for the prevention and treatment of cardiac arrhythmias.

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4
Q

Glycoside inotropic drugs

A

these are cardiotonic agents of natural origin, the nitrogen-free molecules of which consist of two parts connected by an ether linkage

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5
Q

Glycoside inotropic drugs consist of two parts connected by an ether linkage:

A

Glycon - provides the pharmacokinetics of cardiac glycosides (polarity, solubility in water, lipids and ability to cumulate)
Aglycone - structure, providing pharmacodynamics

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