Cardiac effects of cardiac glycosides: Flashcards
The positive inotropic effect of cardiac glycosides
- Increase the strength and speed of myocardial contraction.
- stroke and minute volumes of blood circulation increase.
- Due to a decrease in the end-systolic and end-diastolic -volumes of the heart, its size is reduced and the need for this organ in oxygen is reduced
The negative chronotropic effect of cardiac glycosides
is characterized by a decrease in heart rate due to a decrease in the automatism of the sinus node. This occurs as a result of an increase in the tone of the vagus nerve upon stimulation of the baroreceptors of the aortic arch and carotid sinus.
The negative dromotropic effect of cardiac glycosides
is manifested in the lengthening of the refractory period of the atrioventricular node, therefore, the number of impulses passing through this compound per unit of time decreases. Due to this effect, cardiac glycosides are prescribed for atrial fibrillation
The batmotropic effect
alters the excitability of the membrane of the heart muscle cells, thereby facilitating the formation of an action potential. Positive batmotropic effect results in increased excitability of the heart.