Classification of Cardiotonic Drugs

Question 1

Classification of Cardiotonic Drugs I

Answer 1

I. - with 5-carbon lactone ring - “cardenolides»:

Question 2

Classification of Cardiotonic Drugs II

Answer 2

II. - with a 6-carbon lactone ring - “baph-dienolide”:

Question 3

I. - with 5-carbon lactone ring - “cardenolides»: 1

Answer 3

Non-polar (lipophilic - contain 1 hydroxyl group) - Digitoxin

Question 4

I. - with 5-carbon lactone ring - “cardenolides»: 2

Answer 4

Moderately polar (contain 2 hydroxyl groups) - Digoxin (Lanikor), Lanatozid C (Celanid, Izolanid)

Question 5

I. - with 5-carbon lactone ring - “cardenolides»: 3

Answer 5

Polar (water soluble - 4-5 hydroxyl groups) - Strophanthin K, Ouabain (Strofantin G), Korglikon

Question 6

II. - with a 6-carbon lactone ring - “baph-dienolide”:

Answer 6

Sea onion remedies - Meproscillarine (Clift) – do not reduce HR, CG of hellebore and toad skin glands secretion (Bufo)