Definitions Flashcards
Agonists
Receptor ligands which bind and then stimulate and effect
Antagonist
Receptor ligands which bind and don’t stimulate an effect (stops normal hormone binding)
Phenotype
Observable characteristics of an individual resulting from the interaction of its genotype (genetic material) with its environment
A specific variable characteristic that’s observed
Genotype
The genetic make up of an organism
The genetic constitution of a characteristic
Dysphagia
Difficulty swallowing
Asphyxia
Starvation of oxygen cause coma, death or suffocation e.g from choking
Incidence
Number of NEW disease cases in a given population in a given time frame
Prevalence
The proportion of a given population with a disease at a given time point.
Tachycardia / tachyarrhythmia
Fast heart rate
Resting heart rate above 100 bpm
Bradycardia
Slow heart rate under 60 bpm
Atrial fibrillation
Abnormal heart rhythm - rapid / irregular
Major cause of stroke
Electrical impulses fired from different places in the heart which override the hearts natural pacemaker
Heart arrhythmia
Irregular heart beat (bradycardia and tachycardia come under this)
Morbidity
The condition of being diseased
Epidemiology
Study of the distribution of health conditions in defined populations.
Polydipsia
Thirsty
Polyuria
Urinating more - particularly at night
Normally body temp
37 degrees Celsius
Skin turgor
Elasticity of skin
Hypertension
High blood pressure
Polyphagia
Excessive hunger
Paresthesia
Burning or prickling sensation - tingling or numbness
Retinopathy
Common cause of vision loss
Damage to retina
Peripheral neuropathy
Damage to peripheral nerves
Nephropathy
Kidney disease or damage
Tachypnoea
Abnormally rapid breathing
Tachycardia
Tachyarrhythmia
Heart rate above normal (over 100 beats per mins)
Apnoea
Muscles in throat relax during sleep which temporarily makes the patient stop breathing
Stridor
High pitched wheezing sound
Angina
Temporary chest pain, pressure or discomfort
Hypertropy
Increase in size of skeletal muscle
Hyperplasia
An abnormal increase in the amount of organic tissue resulting from cell proliferation
Atrophy
Wasting away
Hypoplasia
Underdevelopment of a tissue
Metaplasia
Abnormal change in the nature of the tissue
Ectopia / heterotopia
A tissue/organ in the wrong physiological place
Hypoxia
Low tissue oxygen
Hypoxemia
Low blood oxygen
Syncope
Temporary loss if consciousness due to insufficient blood flow to the brain
Myalgia
Muscle pain
Malaise
Discomfort
Calor
Dolor
Rubor
Tumor
Heat
Pain
Redness
Swelling
Anabolic
Small to large molecules
Catabolic
Large to small molecules
Cholestasis
Cholestasis is defined as a decrease in bile flow due to impaired secretion by hepatocytes or to obstruction of bile flow through intra-or extrahepatic bile ducts. Therefore, the clinical definition of cholestasis is any condition in which substances normally excreted into bile are retained.