DEFERRALS Flashcards
• History of parenteral drug use
PERMANENT DEFERRAL
• Received clotting factor concentrate
PERMANENT DEFERRAL
• High-risk occupation (i.e., prostitution)
PERMANENT DEFERRAL
• Positive test for HBsAg
PERMANENT DEFERRAL
• Positive Viral Hepatitis since 11 years of age
PERMANENT DEFERRAL
• Presence of HCV, HTLV, HIV infection
PERMANENT DEFERRAL
• Risk factors for Creutzfeldt-Jakob disease (prions) or who have an immediate family with CJD
PERMANENT DEFERRAL
• Received human-derived growth hormonel corneal/ dura mater
PERMANENT DEFERRAL
• Received a xenotransplantation
PERMANENT DEFERRAL
• Received bovine insulin (Mad cow disease)
PERMANENT DEFERRAL
• Used Tegison (treatment for psoriasis; considered teratogenic or may cause developmental or congenital malformation)
PERMANENT DEFERRAL
• Autoimmune disease
PERMANENT DEFERRAL
• Men-to-men sexual contact since 1977
INDEFINITE DEFERRAL
• Men & women engaged in sex for money/drug since 1977
INDEFINITE DEFERRAL
• CJD or vCJD-related deferrals
INDEFINITE DEFERRAL
Blood relative of someone diagnosed with CJD or vCJD
INDEFINITE DEFERRAL
Who spent 3 months in UK from 1980 through 1996
INDEFINITE DEFERRAL
Spent 5 years in Europe from 1980 to the present
Spent 5 years or more in France from 1980 to the present
INDEFINITE DEFERRAL
For persons who served in the U.S. military, who spent 6 months or more in Northern Europe (Germany, UK, Belgium, the Netherlands) from 1980 to 1990 or spent 6 months or more from 1980 to 1996 in Greece, Turkey, Spain, Portugal, or Italy.
INDEFINITE DEFERRAL
If a donor received a blood transfusion in the United Kingdom from 1980 to the present
INDEFINITE DEFERRAL
If a donor received bovine insulin since 1980 unless the bovine insulin did not come from the United Kingdom
INDEFINITE DEFERRAL
Those who have received a transfusion of blood, platelets, plasma, cryoprecipitate, or granulocytes in the United Kingdom or France since 1980.
INDEFINITE DEFERRAL
CJD
Creutzfeldt-Jakob Disease
Have Leukemia/Lymphoma or other types of Cancer
INDEFINITE DEFERRAL
Diseases of the blood such as
• hemophilia,
• von Willebrand disease,
• sickle cell anemia,
• thalassemia,
• Kaposi’s sarcoma,
• polycythemia, or a history of receiving clotting factor concentrates
INDEFINITE DEFERRAL
Anyone who was born or lived in any of the African countries on the FDA list of countries with HIV-1 group 0 risk since 1977
INDEFINITE DEFERRAL
Sexual contact with anyone who was born or has lived in Africa
INDEFINITE DEFERRAL
Current List of Countries with HIV-1 Group O Risk
Benin
Cameroon
Central African Republic
Chad
Congo
Equatorial Guinea
Gabon
Kenya
Niger
Senegal
Togo
Zambia
• Contains killed pathogens
• NO risk of disease transmission
• Donor can usually donate immediately or after 24–48 hours if feeling well.
Inactivated Vaccine
Influenza,
Hepatitis A,
Tdap,
COVID-19 [Pfizer/Moderna]
Inactivated Vaccine
• Contains weakened live organisms
• There is a small risk of viral shedding
• Donor is usually deferred for 2–4 weeks, depending on the specific vaccine.
Live-Attenuated Vaccine
e.g., MMR,
Varicella,
Yellow Fever,
BCG,
Intranasal Flu
Live-Attenuated Vaccine
• Uses a harmless virus to deliver a genetic code to the body
• If non-replicating, donors are usually eligible after 48 hours
• If replication-competent, deferral period may be longer, usually around 2–4 weeks
Viral Vector Vaccine
e.g., AstraZeneca,
Johnson & Johnson COVID-19 vaccines
Viral Vector Vaccine
