Deep Vein Thrombosis Flashcards
Virchow’s triad
- stasis of blood flow
- endothelial injury
- hypercoagulability
Underlying pathological change in DVT
++ procoagulant:anticoagulant
Which syndrome is associated w/ recurrent miscarriages and causes hypercoagulability state
Antiphospholipid syndrome
Why are some women at higher risk of DVT
Combined oral contraceptive
Which factor is a RF for DVT
F V Leiden
DVT clinical features
- unilateral warm, swollen calf
- pain on palpitation
- pitting oedema
- dilation/distension of superficial veins
- red/discoloured skin
- > 3cm diff between calves
- PE symptoms
Next step if well’s score <2
Quantitative D-dimer level
When is D-dimer produced
Clot breakdown
Next step if well’s score >2
Doppler US
What to do if you have -ve scan & +ve D-dimer
Stop DOAC & repeat Ix in a week
Initial management for suspected/confirmed DVT
- apixaban
- rivaroxaban
Initial management for iliofemoral DVT
Catheter-directed thrombolysis
Long term DVT management meds suitable in most patients
DOACs
Long term DVT management med that is 1st line in antiphospholipid syndrome
Warfarin
Long term DVT management med that is 1st line in Preggo
LMWH
