deck_3487113 Flashcards

1
Q
  • absence of melanocytes

* causes depigmentation

A

Vitiligo

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2
Q
  • associated with defects in collagen support structure of dermis
A

Ehlers-Danlos Syndrome

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3
Q
  • location: flexor surfaces in adults
  • etiology: filaggrin mutation
  • associated with asthma and allergic rhinitis
  • staph aureus is suggested to exacerbate this disorder
  • in children, is on cheecks and extensor surfaces
  • eczema is type of atopic dermatitis
A

Atopic Dermatitis

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4
Q
  • type of atopic dermatitis
A

Eczema

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5
Q
  • etiology: common irritants
A

Irritant Contact Dermatitis

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6
Q
  • etiology: common allergens
  • delayed type hypersensitiviey reaction (type 4)
  • diagnosis confirmed with patch testing
  • skin biopsy would reveal spongiotic dermatitis
A

Contact Dermatitis

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7
Q
  • location: lower legs

* etiology: lower extremity edema

A

Stasis Dermatitis

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8
Q
  • same as nummular eczema
  • round, annular, scaly plaques
  • due to dry skin
  • overuse of soap can make this worse
A

Numular Dermatitis

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9
Q
  • location: scalp
  • etiology: malassezia furfur
  • also known as cradle cap
  • infection of sebaceous glands
A

Seborrheic Dermatitis

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10
Q
  • location: extensor surfaces
  • may include arthritis
  • may be associated with increased cardiovascular risk
A

Chronic Plaque Psoriasis

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11
Q
  • skin cancer
  • most common
  • pearly
  • common on nose
  • tx: mohs surgery, vismoedgib (blocks smoothend gene)
A

Basal Cell

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12
Q
  • second most common skin cancer
  • occurs more common in immunosupporessed pts keratoacanthoma is a type of this cancer
  • center crater
  • develop rapidly
  • on sunexposed skin, HPV, thermal injury
  • actinic keratosis is premalignant skin lesion
A

Squamous Cell

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13
Q
  • skin cancer
A

Melanoma

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14
Q
  • often associated with immunodeficiency
A

Kaposi Sarcome

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15
Q
  • can be treated with beta blockers
  • most common benign soft tissue tumor of infants
  • GLUT1 positive
A

Infantile Hemangioma

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16
Q
  • associated with high levels of GLUT-1 expression (a placenta associated marker)
  • also called strawberry hemangioma
A

Infantile Hemangioma

17
Q
  • associated with glaucoma and seizures
A

Port Wine Stain

18
Q
  • linear plaque on the face or scalp
  • yellow-orange
  • associated with allopecia
A

Nevus Sebaceus

19
Q
  • most commonly on face>trunk>extremity

* beign tumor of oil gland

A

Sebaceus Hyperplasia

20
Q
  • from fibroblast
  • firm papule
  • most common on legs
  • dimple sign is characteristic
A

Dermatofibroma

21
Q
  • scar gowth above and beyond original border
A

Keloid Scar

22
Q
  • sudden appearance associated with adenocarcinoma of the stomach
A

Seborrheic Karatosis

23
Q
  • flat macules

* palms and soles most common

A

Junctional Nevus

24
Q
  • more common in asians and causcasians
A

Blue Nevus

25
Q
  • biggest risk factor for melanoma
  • familial atypical moles and melanoma criteria: The occurrence of malignant melanoma in 1 or more first- or second-degree relatives The presence of numerous (often >50) melanocytic nevi, some of which are clinically atypical Many of the associated nevi showing certain histologic features CDK2NA mapped to 9p21 CDK4 mapped to 12q14 CMM1 mapped to 1p
A

FAMMM Syndrome

26
Q
  • six or more cafe au lait spots
  • two or more neurofibromas
  • axillary or inguinal freckling (Crowe’s sign)
  • first degree relative with disorder
  • autosomal dominant
A

Neurofibromatosis

27
Q
  • multiple lesions associated with neurofibromatosis
A

Cafe au Lait Patch

28
Q
  • melassezia furfur is causative agent
A

Tinea Versicolor

29
Q
  • acquired disease involving antibodies to cell-to-cell adhesion molecules in the stratum spinosum (keratinocytes)
  • attacks desmosomes
A

Permphigus Vulgaris

30
Q
  • vitamin cross links tropocollagen together
  • this disease is characterized by lack of vitamin C
  • SS: keratotic plugging of hairs, corkscrew hairs, hemorrhagic gingivitis
A

Scurvy

31
Q
  • type 2 antibody mediated

* detachment between dermis and epidermis- hemidesomsomes

A

Bullous Pemphigoid

32
Q
  • do not debride

* tx with steroids and immunosuppression

A

Pyoderma Gangrenosum

33
Q
  • associated with hepatitis
A

Lichen Planus

34
Q
  • with internal malignancies, pts tend to have weight loss- most common is stomach cancer
  • thickening of the skin
  • common causes: obesity, diabetes
A

Acanthosis Nigricans

35
Q
  • filagrin mutation
A

Icthyosis Vulgaris

36
Q
  • honey colored

* associated with strep and staph

A

Impetigo