deck_1357021 Flashcards
Cell Membrane Components
Phospholipids, proteins, cholesterol
Phospholipids
membranes are variously composed of these special lipids, they are amphipathic molecules with a hydrophobic and phillic end can assemble as micelle, bi-layer and liposome
glycolipids
carbohydrate branches attached to exterior end of lipid
glycoprotein
carbohydrate attached to the exterior end of a protein in the cell membrane
Proteins
functional part of the membrane, there are 2 kinds of membrane proteins: Integral Membrane proteins and Peripheral membrane proteins
Integral membrane proteins
regions of lipid sea, held in position
Peripheral membrane proteins
located on the surfaces of the lipid sea usually on the cytoplasm side
Kinds of membrane proteins
structural - give cell structural integrity, ECMchannels - allow for passive transport of molecule through membranetransporters - active transport of molecule along natural conc gradientpumps - active transport of molecule against concentration gradienttransducers - couple a membrane receptor to cytoplasmic enzymeenzymes - perform cellular work by catalyzing rxn
Cholesterol
added agent involved in cell fluidity, amphipathis steroid, enhances cell membrane stability decreases permeability, helps with packing the phospholipids.
Fluis Mosaic Model
protein and lipid distribution is assymetrical, membrane must be able to engage in recognition, transportation and communication.
Membrane recognition
cellular adhesion, cellular interactions with prokaryotic organisms, cellular/tissue identity, cellular immunity
cellular adhesion during growth and development
by cellular density/contact with cell beside it, the part that is recognizable is the stage-specific embryonic antigens (SSEA’s)
cellular adhesion in mature tissues
cell adhesion molecules (CAM’s) are what join the cells together
cadherin
link cells to identical cells
integrin
links cells to the ECM