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PID Exams > deck 11 > Flashcards

deck 11 Flashcards

1
Q

What 3 bacteria should we usually think about in the case of purpura fulminans?

A

Group A strep (S. pyogenes)Staphylococcus aureusNeisseria meningiditis(Also remember he said bacillus cereus had also been identified as a cause!)

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2
Q

If you had all the drugs/interventions you needed for the following case…what would you use? [7 items]-104.5 T, BP 60/0, purpuric rash, 3day vomit/diarrhea, highly elevated liver/kidney enzymes, very low calcium/platelets.

A

vancomycinrifampinclindamycinIVIGvasopressorsFluid and electrolytesdrotrecogin alpha

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3
Q

In the case where the man had a near death experience twice with the same bacteria, they found his family to have beta-hemolytic streptococcus group G not group A. What did they treat the family with? [3 drugs]

A

ceftriaxoneclindamycinrifampin

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4
Q

In the case where the man had a near death experience twice with the same bacteria, they found his family to have beta-hemolytic streptococcus group G not group A. Why did he get effected and not everyone else?

A

He lacked antibodies to SPEA and SPEC

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5
Q

In the case where the man had a near death experience twice with the same bacteria, they found his family to have beta-hemolytic streptococcus group G not group A. Once they found out what the issue was, how did they treat him?

A

Monthly IVIG for a year.

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6
Q

What type of drugs are used for T cell lymphoma?

A

cytotoxic drugs

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7
Q

What drug is used to treat USA200 CA-MRSA?

A

vancomycin

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8
Q

What is used in the treatment neutralizing TSST-1?

A

IVIG

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9
Q

Gram +, cocci, beta-hemolytic, catalase negative point to what bacteria?

A

streptococci

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10
Q

What is the final identification test for streptococci bacteria?

A

lancefield grouping

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11
Q

How many serotypes are found in group B strep? What is their serotypes based on?

A

9capsular polysaccharide

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12
Q

How many women are colonized vaginally with group B step? group A strep?

A

20-40%1/100-1%

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13
Q

T-F– humans acquire group B streptococci from cows/milk?

A

False

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14
Q

What causes bovine mastitis?

A

Group B strep

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15
Q

What is a major way Group B strep is transmitted? What is the relatively less common mode of transmission?

A
  1. fetus and neonate from women vaginally colonized.2. direct contact with breaks in the skin for TSS
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16
Q

When is group B strep routinely assessed/screened for?

A

third trimester

17
Q

How are pregnant women colonized with group B strep treated?

A

penicillin to reduce colonization

18
Q

What are the 3 cell surface virulence factors of group B strep

A
  1. antiphagocytic caps. polysaccharide.2. C5a peptidase3. Surface proteins alpha and beta
19
Q

How many cases of early onset sepsis with group B strep occur in the US each year?

A

10,000

20
Q

What is the outcome of fetal/neonate sepsis of group B strep?

A

30-50% fatality

21
Q

True or false- neonates do not show fever often?

A

true

22
Q

What is a very important sign of bacterial infection in neonates?

A

lethargy

23
Q

How many cases of late onset meningitis from group B strep happen in the US/ year?

A

10,000often seen in neonates greater than 5 days but less than one year

24
Q

What are the 2 types of vaccines being developed for group B strep.?

A
  1. capsular polysaccharides (type specific)2. C5a peptidase (not type specific)
25
Q

T-F—group C strep will often cause pharyngitis, but group G will not?

A

False—both can cause pharyngitis

26
Q

T-F—group G strep can cause toxic shock syndrome, but group C never does?

A

False—both can cause

27
Q

What is the name of group D strep?

A

Streptococcus bovis

28
Q

T-F—group D strep is beta hemolytic?

A

Falseit is either non-hemolytic or alpha hemolytic

29
Q

What is group D strep often associated with?

A

gastrointestinal malignancy[not known if it is the cause or grows as the result of]

30
Q

What 3 things is streptococcus bovis occasionally associated with?

A
  1. endocarditis2. UTI3. sepsis
31
Q

What is the function of the surface proteins alpha and beta in group B strep?

A

unknown but it is known they are required for virulence.

PID Exams (17 decks)

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