Deck 1 Flashcards
Question
Explanation
what do you do for infacnts with brachial plexus injury
you just observe them and can do physical therapy
what causes irregular menses and anovulatory bleeding in adolescesnts
immature HPA axis
what population of HIV patients get HIV associated dementia
patients with uncontrolled HIV that are not on ART
skin findings of NF1
cafe-au-lait spots, axillary and inguinal freckling, lisch nodules
tumors associated with NF1
optic glioma, pheo, neurofibromas
skin findings NF2
skin nodules (schwannomas)
tumors associated with NF2
bilateral vestibular schwannoma
skin findings tuberous sclerosis
multicle facial adenomas, ash-leaf spots, shagreen patchs, ungual fibromas
neuro findings tuberous sclerosis
seizures, intellectual disability
tumors associated with tuberous sclerosis
hamartomas, giant cell astrocytoma, cardiac rhabdomyomas, renal angiomyolipoma, cysts and RCC
findings of von-hippel lindau disease
cerebellar and retinal hemangioblastomas, pheo, RCC
what color does blood show on non contrast CT
white
what is bright in T1 weighted MRI
fat and contrast
what is bright in T2 weighted MRI
water (CSF), and fat (but less intense than T1)
flesh colored raised papules in anogenital area
condyloma accuminata (HPV)
sudden decline in development of a young girl
Rett syndrome
signs of Rett syndrome
gait disturbances, sudden decline in development, hand movements, loss of speech
signs of myotonic dystrophy
myotonia and weakness, distal mm atrophy
complications of myotonic dystrophy (heart)
cardiomyopathy, arrythmias,
if a vertebral body goes forward what joint get dislocated
facet joint dislocation
what brain issues do people with ADPCKD get
aneurysms (berry)
what is associated with difficulty with an upward gaze
pinealoma
functional tremor signs
abrupt stopping in the tremor, stops with distraction, changeable features of the tremor
where do neuroblastomas arise
adrenal medulla or along the sympathetic chain
where do medulloblastomas arise
in the cerebellum
clinical features of neuroblastoma
opsoclonus-myoclonus, periorbital eccymosis, abdominal mass
clincal features of medulloblastoma
cerebellar signs (gait changes, central uncoordination), hydrocephalus
what cervical nerve is injured if patient has claw hand and wrist extension
C8 and T1
are antipsychotics safe in pregnancy
yes, use for acute mania
dx of a fluid collection spanning multiple vertebra on MRI
spinal epidural abcess
treatment of spinal epidural abcess
ABX and urgent laminectomy
what is most specific to seizure activity
tongue biting
treatment of organophosphate poisoning
atropine and then pralidoxime
what is physostigmine
achetylcholineesterase inhibitor
complications of asymptomatic bacteruria of pregnancy
pyelo or preterm labor
what nerve can be compressed with uncal herniation
occulomotor (CNIII)
what type of brain hernation occurs after epidural hematoma
uncal
signs of pelvic organ prolapse
any mass that increases in size with valsalva
what is the main defining feature of PTSD
exposure to a life-threatening trauma
difference between rathkes cleft cyst and craniopharyngioma
craniopharnygioma will have calcifications seen on imaging
day and night time eneureis in children with red flags eval
MRI
treatment of NPH
high volume lumbar puncture
what does the head thrust test evaluate
vestibuloocular reflex
what happens to TSH during pregnancy
decreased because HCG stimulates thyroid hormone production so TSH decreases bc neg feedback
presentation of conus medullaris vs. cauda equina pain
conus medullaris is severe low back pain and cauda equina is radicular pain (down leg
presentation of conus medullaris vs. cauda equina upper motor or lower motor neuron signs
conus medullaris has upper motor and cauda equina has lower
presentation of conus medullaris vs. cauda equina bladder symptoms
both have bowel and bladder dysfunction because of pudendal nerve
alcohol withdrawal vs. thiamine deficiency differentiation
alcohol withdrawal has autonomic instability and thiamine is more of an encephalopathy
central cord syndrome signs
sensory distubances in upper extremities, upper extremity weakness because the corticospinal tract has arms closest to the center of the cord
1hr glucose tolerance test cutoff
200
do absence seizures have a postictal period
no!
best form of emergency contraception
IUD and then levonorgestrel
time course for alteplace/TNK for stroke
<4.5 hours
signs of PTSD in kids
emotional dysregulation, play that imitates trauma, nightmares
signs of reactive attachment disorder
lack of emotional responsiveness, no seeking of comfort from caregivers
what causes reactive attachment disorder
early childhood abuse
what types of hemorrhage is cause by nonaccidental trauma
subdural and retinal hemorrhage
what is pituitary apoplexy
hemorrhage or acute ischemia of the pituitary causing acute adrenal insufficiency
what is the most common childhood brain tumor
low-grade astrocytoma
what do you use for benzo overdose
flumenazil
what does elevation of the diaphragm on chest xray typically indicate
this means that there is diaphragmatic weakness likely from ALS
why do pts with spinal cord injurys get autonomic dysreflexia
because the parasympathetic response cannot be sent down the spinal cord
noxious stimulus below a spinal cord injury effects
you get autonomic dysreflexia which means you get sweating, palpitations, etc, above the lesion and
clinical signs of sturge webber
seizures, port wine stain, glaucoma,
signs of methamphetamine intoxication vs. acute manic disorder
meth often has severe dental symptoms, more tactile hallucinations, and skin excoriations vs. mania which is more grandiose delusions and no sympathetic overdrive
PML on imaging
multiple NON enhancing lesions
new onset psychosis plus tremor/parkinsonism
wilsons diseaseI
pH of genitourinary syndrome of menopause
elevated pH (6.5) due to decreased vaginal secretions that are acidic
CNS lesions in tuberous sclerosis
subependymal tumors, giant cell astrocytoma, etc
where are brachial cleft cysts on the neck
lateral
difference between nightmare disorder and sleep terror disorder
nightmare the child is fully aware and they are able to communicate but in sleep terror disorder they are not aware and have amnesia
long term complication of delerium
cognitive decline
main difference between serotonin syndrome and neuroleptic malignant syndrome
serotonin syndrome has hyperreflexia vs. NMS is just rigidity
4 clinical manifestations of IgA vasculitis
palpable purpura, arthralgia/arthritis, abdominal pain, renal disease
signs of cerebellar dysfunction
truncal or gait ataxia, wide-based gait, poor heel-toe coordination
what happens with blood pressure in TRALI
tanks
is INO ipsilateral/contralateral in terms or MLF lesion to eye not adducting
ispilateral
orthopedic signs of tethered cord
back pain, scoliosis, foot deformities
is a sputum cytology helpful for cancer dx
no!
difference between illness anxiety disorder and somatic symptom
illness anxiety is where you have preoccupation with having a serious illness vs. somatic symptom disorder you have unexplained symptoms and anxiety around the symptoms
treatment of stroke in sickle cell
exchange transfusion
5-alpha reductase defiency genotype
46 XY
5 alpha reductase signs
virulization at puberty due to increased testosterone (acne, cliteromegaly, increased muscle mass, male pattern hair)
treatment of phantom limb pain
multimodal, antidepressants, CBT etc.
return to sports after concussion timeline
rest for 2 days, gradual progression of activity with return to rest if there is headaches etc.
who gets cyclic vomiting syndrome
people with migraines or fam hx of, identifialble triggers like stress
timeline for adjustment disorder
sx onset within 3mo of an identifiable stressor
management of hyaditiform mole after curretage
month B-hcg levels and 6mo of contraception
physical exam of a patient with cervical insufficiency
shortened cervix or dilated cervix, no vaginal bleeding, pelvic pressure
signs of placenta previa
painless vaginal bleeding at >20 weeks gestation
sleep changes in MDD
decreased REM sleep latency, increased REM, decreased non-rem, multiple nighttime awakenings
5 P’s of acute intermittent porphyria
painful abdomen, polyneuropathy, psychologic disturbances, port wine pee, precipitated by drugs
can scfe be bilateral
yes
pain with internal rotation in a child with hip pain
SCFE
management of frostbite
rapid warming, angiography if rewarming not successful
triad of wiskott aldrich
recurrent infections, eczema, purpura
what is transient hypogammoglobulinemia of infancy
this is when the infant has delayed rise in IgG after physiologic nadir after 6mo of age, will resolve
ultrasound findings of placenta accreta
US with placenta previa, numberou lacunae, myometrial thinning
what is considered adequate contractions
> 200 montevideo units
dx of hirschsprungs
biopsy, contrast enema, anorectal manometry
who gets uterine rupture
patients with previous uterine surgeries
what does the uterus feel like in uterine rupture
can feel palpable fetal parts
clinical presentation of placental abruption
sudden onset vaginal bleeding, abdominal pain, high freq/low intensity contractions, rigid uterous
when do you do a ERCP for pancreatitis
if there is CBD dilation indicating stone or evidence of acute cholangitis
management of gallstone panc after panc resolved and no cholangitis/biliary issue
cholecystectomy once pancreatitis resolved
treatment of periorbital hemangioma in infant
propanolol
treatment of port wine stain
laser (cosmetic)
can you give metronidozole in pregnancy
Yace
treatment of binge eating disorder
SSRI
signs of NMDA (ecstacy) toxicity
sympathomimetic tox and serotonin sydrome and hyponatremia
signs of blunt thoracic aortic injury
bruising on the chest, weak femoral pulses, cool limbs, proximal hypertension
what is aspirin exacerbated respiratory disease (triad)
asthma, bronchospasm following aspirin use, chonic rhinosinusitis with nasal polyps
treatment of parkinsons tremor
anticholingergic therapy
signs of separation anxiety
reluctance to leave, avoidance of activities, excessive worry
signs of growing pains
worse at night, primarily at night
what does a positive arm drop test mean
rotator cuff tear
what newborns get ABO incompatability hemolytic disease
newborns who are AB that have mothers who are O
in a neonate with cyanosis does their O2 sat change when they are given oxygen if it is a heard issue
no it wont change so if it increases they have a pulmonary pathology
effects of gestational diabetes on fetal lungs
immaturity, poor surfactant maturation
what are pulses like in aortic regurg
wide pulse pressure
treatment of NEC
stopping enteral feeds, fluids, BCX and then ABX, if no improvement or has bowel perf, then surgery
treatment of migraine in pregnancy
acetominophen, antiemetics, NSAIDs, opioids
treatment of croup
dexamethasone and racemic epinephrine
when does uric acid precipitate from the urine
it precips at low pH <5.5
why do crohns or CF patients get Ca oxalate stones
because they absorb less Ca and Ca binds oxalate in the intestine so more oxalate gets absorbed and then excreted in the kidney which causes increased Ca oxalate stones
treatment of frequent uric acid stones due to gout
alkalinazation of the urine
what part of the brain gets atrophy in alzheimers
temporal lobe (with the hippocampus and amygdala
signs of croup
barking cough, hoarseness, inspiratory stridor
signs of babeosis
flu like sx, DIC, anemia, thrombocytopenia, increased bili, LDH etc.
consequenses of preeclampsia
ischemic stroke, seizures, AKI, hepatic subcapsular hematoma, ARDS, placental abruption
signs of central brain herniation
decorticate to decerebrate posturing
why do you get thrombocytopenia in SLE
peripheral destruction due to immune thrombocytic purpura
can you hear a bruit on exam for aortic aneurysm
no
what do nitrates do to the heart
they decrease preload which decreased left ventricular end diastolic volume because of venous dilation
which is external vs. internal in CNIII for parasympathetic vs. motor
external is parasympathetic and internal is motor
is parasympathetic or motor (somatic) fibers more susceptible to ischemia
motor because the center of the nerve is more susceptible to ischemia because the blood vessel is on the outside
granulomatosis with polyangiitis pulmonary findings
ulceration, lung nodules with cavitation
signs of retinal detachment in the history
flashes of lights, dark spots or webs, floaters, peripheral vision defects
describe odds ratio
the odds that an event with occur in one group vs. the odds of an event occuring in another group
describe risk ratio
the likelihood of an outcome in one group exposed to a potential risk factor compared to the risk in another unexposed group
what is considered macrocephaly
> 97th percentile
what is the uterus like in adeomyosis
symetrically enlarged and painful
what is the mutation in CML and what is the chromosome
this is chrom 22 which is the BCR ABL gene creating always active tyrosine kinase
differences in TM in acute otitis media vs. otitis media with effusion
AOM has bulging and erythema of the TM whereas otitis media with effusion is not bulging just immobility
management of prepnant people with HSV prior to pregnancy
if they have lesions you do a c section if they are asymtomactic you do antiviral therapy starting at 36 weeks
how do you treat SCFE
screw fixation
size of ovary in torsion
enlarged due to trapped blood flow
CHARGE syndrome
Coloboma, heard defects, choanal atresia, retardation of growth, genitourinary anomalies, ear abnormalities
VACTERL features
vertebral anomalies, anal atresia, cardiac issues, TEF, renal and limb issues
signs of choanal atresia
hypoxia during breast feeding or sleeping that gets better with crying
two main causes of pleural fluid with glucose less than 30mg/dl
rheeumatoid pleuracy or empyema
causes of infectious adrenalitis
TB, CMV, histo
risks for somatic sx disorder
sexual trauma, lower education level, chroic chiIdhood illness, female
signs of mesenteric ischemia
rapid onset periumbilical pain, hematochezia, extreme pain
lab abnormalities in acute mesenteric ischemia
leukocytosis, elevated hemoglobin, elevated amylase, metabolic acidosis
signs of psychosis
delusions, hallucinations, disorganized speech
what is the mutation in fanconi anemia
DNA repair defect
clinical findings of fanconi anemia
short stature, hypo or hyper pigmented macules, abnormal thumbs, genitourinary findings
thyroid changes in pregnancy
TSH goes down (BHCG), free T4 and total T4 goes up
signs of open globe injury
fixed tear drop pupil, relative afferent pupillary defect, decreased intraocular pressure
urticarial transfusion reaction
hives and itching NO RESP DISTRESS
treatment of urticarial transfusion reactions
cessation of transfusion, antihistamines, then resume if theyre well
what is a dupuytren contracture
thickening of palmar fascia at the 3/4/5th digits
neuro sx of B12 deficiency
sensory ataxia, upgoing plantar reflexes, lower extremity paresthesias, neuropsychiatric changes
emypema vs. abscess imaging
empyema is just puss filled NO AIR FLUID LEVEL // abcess has an air fluid level
what is transverse myelitis
this is immune mediated destruction of the spinal cord
clincial features of transverse myelitis
bilateral motor weakness, LMN to UMN symptoms, bilateral sensory dysfunction, autonomic dysfunction
likely dx of a person with fluctuating bulbar weakness
myasthenia gravis
WAGR syndrome
wilms tumor, aniridia, genitourinary abnormalities, range of developmental delays
clinical features of fat necrosis of the breat
firm irregular mass, skin/nipple retraction
signs of urethral injury
blood at urethral meatus, high riding prostate
what does an MECP2 mutation do
rett syndrome (girls X dom, hands)
tay sachs enzyme and common findings
hexosaminidase A and this is severe neurodegeneration and death by 2-5
clinical features of osteogenesis imperfecta
frequent fractures, blue sclera, dentinogenesis imperfecta
symptoms of pelvic organ prolapse
pelvic pressure, voiding dysfunction (incontinence, urinary retention, etct)
what lab abnormality is seen in von willebrand disease
long bleeding time, normal PT and PTT
methotrexate adverse effects
myelosuppression, pulmonary fibrosis, hepatotoxicity, nephrotoxicity,
causes of duodenal vs. jejenal atresia
duodenal is typically failure to recanalize vs. jejenal is due to vascular accident
most common cause of potter sequence in males
posterior urethral valves
where are venous vs. arterial ulcers on the maleoli of legs
venous are on the medial side and arterial are on the lateral maleolus
first step in evaluation of hypospadias
karyotype analysis
features of disseminated neisseria gonorrhea infection
skin manifestations, tenosynovitis, polyarthralgias, purulent arthritis
what mutation causes osteosarc and retinoblastoma
Rb
frequent bronchitis, pneumonia and bronchiectasis
common variable immunodeficiency
treatment of wide complex tachycardia
synchronized cardioversion
epidural hematoma shape
lemon aka DOES NOT cross suture lines
which type of hematoma has a lucid interval
epidural hematoma
signs of eosinophilic esophagitis on EGD
circumfrential lesions, strictures, linear longtitudinal furrows
what is the best way to improve burnout
organization directed interventions like scribes, and reducing workload
clinical features of x linked agammaglobulinemia
recurrent pyogenic infections, hypoplastic tonsils, absent B cells on flow
treatment of x linked agammaglobulinemia
IV immunoglobulin therapy
which is associated with IBD PSC or PBC?
PSC!!!
pathology of PSC
inflammation and fibrosis of intra and EXTRA hepatic ducts, strictures and dilatations
pathology of PBC
autoimmune destruction of intrahepatic dugs, lymphocytic infiltration of portal areas and granulomas
how are becker/duchenne dx
genetic analysis, only do mm bx if genetics inconclusive!
respiratory changes in pregnancy
respiratory alkalosis due to increased minute ventilation to facilitate gas exchange at the placenta
what is the depot shot made of
progesterone, hypercoag ppl can take it
definition of mood disorder with psychotic features
this is like MDD or bipolar with psychosis DURING the manic/depressive episode, you dont see the psychosis anytime else