Deciding what vector is best for gene therapy Flashcards
1
Q
Uses double stranded DNA
A
Adenovirus and Herpes Simplex virus
2
Q
Uses single stranded DNA
A
Adeno-Associated Virus
3
Q
Uses RNA
A
Retrovirus
4
Q
Retrovirus EG
A
HIV
5
Q
Adenovirus EG
A
Common cold
6
Q
Adeno-associated virus EG
A
Nonpathogenic
7
Q
Herpes Simplex virus EG
A
Oral/genital herpes
8
Q
Infects neurons and the nervous system only
A
Herpes simplex virus
9
Q
Only infects dividing cells
A
Retrovirus
10
Q
Infects dividing and nondividing cells
A
Adenovirus and Adeno-associated virus
11
Q
Remains in cells as plasmid DNA
A
Herpes simplex virus
12
Q
No immune response
A
Adeno-associated virus
13
Q
Max insert size 5k base pairs
A
Adeno-associated virus
13
Q
Max insert size 5k base pairs
A
Adeno-associated virus
14
Q
Max insert size 8k base pairs
A
Retrovirus
